discontinued

AP11876PU-N T1A-2 (N-term) antibody

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0.1 mg / €335.00

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Rabbit anti Human T1A-2

Product Description for T1A-2

Rabbit anti Human T1A-2.
Properties: (N-term)
Presentation: Purified
Product is tested for Paraffin Sections.

Properties for T1A-2

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms HT1A-1, hT1a-1, lung type-I cell membrane-associated glycoprotein
Presentation Purified
Reactivity Hu
Applications P
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human T1A-2.
Property N-term
Add. information Molecular weight: 16684 Da
Application ELISA 1:1,000.
Immunohistochemistry 1:50 - 1:100.
Background Expressed at the plasma membrane in epithelia involved in fluid transport, including type I alveolar epithelial cells, choroid plexus, and ciliary epithelium, the specific function of this protein has not been determined but it has been proposed as a marker of lung injury. T1A-2 has a broad tissue distribution with strong expression in lung, placenta and skeletal muscle. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor.
Concentration 0.25 mg/ml
General Readings
  1. Kato, Y., et al., J. Biol. Chem. 278(51):51599-51605 (2003).
  2. Ma, T., et al., Am. J. Respir. Cell Mol. Biol. 19(1):143-149 (1998).
  3. Zimmer, G., et al., Biochem. J. 341 (Pt 2), 277-284 (1999).
Storage Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Buffer System:
PBS with 0.09% (W/V) sodium azide
State:
Liquid Ig fraction
Purified
Specificity
Specificity:
This antibody detects Podoplanin / GP36 /TIA-2 at N-term.
Species:
Human.

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