discontinued

GTX13517 Tapasin antibody

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50 µl / €310.00

Quick Overview

Rabbit anti Hamster, Human, Monkey, Mouse, Rat Tapasin

GTX13517

Product Description for Tapasin

Rabbit anti Hamster, Human, Monkey, Mouse, Rat Tapasin.
Presentation: Serum
Product is tested for Western blot / Immunoblot.

Properties for Tapasin

Product Category Primary Antibodies
Quantity 50 µl
Presentation Serum
Reactivity Hst, Hu, Mky, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide: KSLSLLLAVALGLATAVSA , corresponding to amino acids 2-20 of Human Tapasin.
Application WB
Background This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
Storage Keep as concentrated solution. Store at 4
Format
Purification:
Whole antiserum
Buffer System:
Preservative: NoneConstituents: Whole Serum
Purity:
Whole antiserum
State:
Serum
Specificity
Specificity:
Cross-reacts with Human, Mouse, Rat, Cow, Dog, Hamster, Monkey and Pig. Not yet tested in other species.

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