discontinued

NBP1-05003 Taxol antibody

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Search for all "Taxol"

0.25 ml / €390.00

Quick Overview

Rabbit anti Human Taxol

NBP1-05003

Product Description for Taxol

Rabbit anti Human Taxol.
Presentation: Serum
Product is tested for Enzyme Immunoassay.

Properties for Taxol

Product Category Primary Antibodies
Quantity 0.25 ml
Synonyms Paclitaxel
Presentation Serum
Reactivity Hu
Applications E
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Application ELISA, The antibody titer is more than 10K for ELISA. It has not been tested in the other applications. However, for the first testing, we recommend 1/1,000 dilution for ELISA, 1/500 dilution for Western blot analysis (WB) of recombinant protein, 1/100 dilution for tissue extracts or cell lysates, 1/100 dilution for immunohistochemistry (IHC) staining on frozen cryosections or paraffin embedded sections., ELISA
Background Taxol (paclitaxel) is particularly effective as an anticancer agent because tubulin is not its only target. It also binds to a protein called Bcl-2, which normally blocks the process of apoptosis, or cell death. Taxol therefore plays a dual role in destroying dividing cells, firstly by stabilizing assembled microtubules and thereby halting mitosis, and secondly by inhibiting Bcl-2 and allowing apoptosis to proceed.
General Readings
  1. Marone M, D'Andrilli G, Das N, Ferlini C, Chatterjee S, Scambia G. Quercetin abrogates taxol-mediated signaling by inhibiting multiple kinases. Exp Cell Res. 2001 Oct 15;270(1):1-12. PubMed PMID: 11597122.
  2. Amos, L.A., Lowe, J. How Taxol stabilises microtubule structure. Chem Bio 1999; 6(3):R65-9
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Whole antisera
Buffer System:
No Preservative
Purity:
Whole antisera
State:
Serum
Specificity
Specificity:
Taxol
Species:
Human

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