TA319883 Tectonic-3 (C-term) antibody

Rabbit Polyclonal TCTN3 Antibody

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0.1 mg / €325.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat Tectonic-3

TA319883

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  • TA319883

Product Description for Tectonic-3

Rabbit anti Human, Mouse, Rat Tectonic-3.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for Tectonic-3

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms C10orf61, TCTN3, TECT3
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q6NUS6
Immunogen:
17 amino acid peptide near the carboxy terminus of human TCTN3
GeneID:
26123
Property C-term
Application ELISA.
Western blot: 1 - 2 µg/ml.
Immunohistochemistry on paraffin sections.
Positive control: SK-N-SH Cell Lysate.
Background TCTN3 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN3 is not known, it is 58% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
Concentration 1.0 mg/ml
General Readings
  1. Reiter JF, Skarnes WC. Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition. Genes Dev. 2006 Jan 1;20(1):22-7. Epub 2005 Dec 15. PubMed PMID: 16357211. (Free PMC Article available, 4 images available)
Storage Store the antibody (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography purified via peptide column
Buffer System:
PBS containing 0.02% sodium azide
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, mouse, rat

Accessory Products

Proteins and/or Positive Controls

Positive controls for Tectonic-3 (1 products)

Catalog No. Species Pres. Purity   Source  

TCTN3 Lysate

Western Blot: TCTN3 Lysate [NBL1-16796] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for TCTN3
  Novus Biologicals Inc.
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