TA349032 TET2 antibody

Rabbit Polyclonal Anti-TET2 Antibody

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0.1 mg / €415.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human, Mouse TET2

Product Description for TET2

Rabbit anti Human, Mouse TET2.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for TET2

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms KIAA1546, Methylcytosine dioxygenase TET2
Presentation Purified
Reactivity Hu, Ms
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Swiss Prot Num:
TET2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human TET2.
Application WB: 1 - 2 ug/mL
Background TET2, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygese that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. It is a candidate tumor suppressor gene reported to be mutated in approximately 14% of patients with JAK2V617F-positive myeloproliferative neoplasms (1), and can be mutated in other hematopoietic disorders such as myelodysplastic syndromes, acute myeloid leukemia, and chronic myelomonocytic leukemia (2). Alysis of the TET2 and JAK2 mutations in these neoplasms suggests that mutations in TET2 do not represent a predisposition for acquiring mutations in JAK2.
TET2 antibody is affinity chromatography purified via peptide column.
Buffer System:
PBS containing 0.02% sodium azide.

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