DM3213 Thymidylate Synthase antibody

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0.1 mg / €270.00

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Mouse anti Human Thymidylate Synthase TS106


Product Description for Thymidylate Synthase

Mouse anti Human Thymidylate Synthase TS106.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot, Flow Cytometry.

Properties for Thymidylate Synthase

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Hu
Applications E, F, ICC/IF, IP, WB
Clonality Monoclonal
Clone TS106
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Biomeda

Datasheet Extract

Recombinant human TS enzyme
Application ELISA (For coating, order Ab without BA). Flow Cytometry. Immunofluorescence. Immunoprecipitation (Native verified): Use Protein G; Ab 2 micrograms/mg protein lysate. Western Blotting: Ab 1-2 micrograms/ml for 2hrs at RT. Immunohistology (formalin/paraffin): Use Ab at 5-10 micrograms/ml for 30 min at RT) -(1:40) Staining of formalinfixed tissues REQUIRES boiling tissue sections in 10mM citrate buffer, pH 6.0. Recommended positive control: 5-FU-resistant cell cancer lines or colon carcinoma. Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
Concentration 0.2 mg/ml
General Readings
  1. Johnston PG, et. al. Cancer Res, 1991, 51(24):6668-76.
  2. Johnston PG, et. al. Cancer Res, 1992, 52(16):4306-12.
  3. Johnston PG, et. al. Biochem Pharmac, 1993, 45:2483-6.
  4. Johnston PG, et. al. J Clin Oncol, 1994, 12(12):2640-7.
  5. Johnston PG, et. al. Cancer Res, 1995, 55(7):1407-12.
  6. Johnston PG, et. al. J Natl Cancer Inst, 1997, 89(4):308-13.
  7. Pestalozzi BC, et. al. J Clin On
Storage Store the antibody at 4°C. Do not freeze! Shelf life: one year from despatch.
Thymidylate Synthase (TS) 1 (EC converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head, neck, and breast carcinomas. Cellular Localization Cytoplasmic, Nuclear.

Mol. Wt. of Antigen: 36kD

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