GTX23145 Thymidylate Synthase [TS 106] antibody

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0.5 ml / €380.00

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Mouse anti Human Thymidylate Synthase [TS 106] TS 106


Product Description for Thymidylate Synthase [TS 106]

Mouse anti Human Thymidylate Synthase [TS 106] TS 106.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot, Flow Cytometry, Paraffin Sections.

Properties for Thymidylate Synthase [TS 106]

Product Category Primary Antibodies
Quantity 0.5 ml
Presentation Purified
Reactivity Hu
Applications F, ICC/IF, IP, P, WB
Clonality Monoclonal
Clone TS 106
Host Mouse
Isotype IgG1
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Recombinant full length protein (Human).
Application FACS, IF, IHC-P, IP, WB
Background Thymidylate Synthase (TS) converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10 methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
Concentration 0.2 mg/ml
Storage Keep as concentrated solution, aliquot and store at 4
Protein G purified
Buffer System:
10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide
Protein G purified
Human - Not yet tested in other species

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