AM03068PU-N Thyrotropin (TSH) antibody

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Mouse anti Human Thyrotropin (TSH) TSH-51


Product Description for Thyrotropin (TSH)

Mouse anti Human Thyrotropin (TSH) TSH-51.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Radioimmunoassay.

Properties for Thyrotropin (TSH)

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Thyroid-stimulating hormone, hTSH
Presentation Aff - Purified
Reactivity Hu
Applications E, ICC/IF, R
Clonality Monoclonal
Clone TSH-51
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Human thyrotropin.
Application Immunocytochemistry.
This antibody TSH-51 is suitable in combination with the antibody TSH-116 (AM03069PU-N) for immunometric assays in the screening of neonatal hypothyroidism.
Background Thyrotropin (hTSH) promotes the growth of the thyroid gland in the neck and stimulates it to produce more thyroid hormones. hTSH is composed of two subunits - alpha and beta.
Concentration 1.0 mg/ml
General Readings
  1. Jirkalová V, Cáp J, Straková H, Príbysová J, Plicka J, Lomský R. Immunoradiometric and luminescence immunoenzymometric assay of human thyrotropin from dried blood spots for screening of neonatal hypothyroidism. Eur J Clin Chem Clin Biochem. 1996 Oct;34(10):823-7. PubMed PMID: 8933106.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Protein A affinity chromatography.
Buffer System:
PBS, pH 7.4 15 mM sodium azide as preservative.
Liquid purified IgG fraction (> 95% pure by SDS-PAGE).
Aff - Purified
The antibody TSH-51 reacts with human thyroid stimulating hormone (hTSH, thyrotropin), a glycoprotein hormone produced by the anterior pituitary gland cells in response to signals from the hypothalamus gland in the brain.
The TSH-51 antibody reacts with association constant 5.5 x 1010 l/mol.
Following cross-reactivity expressed as binding of labelled hormone (% of total) was determined by solid phase RIA with excess of the antibody TSH-51: hTSH (68.6), hCG (0.03), hLH (2.99), hFSH (0.66).

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