AP00233PU-N TIA-1/GMP-17 antibody

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Goat anti Human, Mouse, Rat TIA-1/GMP-17


Product Description for TIA-1/GMP-17

Goat anti Human, Mouse, Rat TIA-1/GMP-17.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for TIA-1/GMP-17

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms GMP17, TIA1
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Goat
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Application The antibody can be used in Western blotting (1-4 μg/ml), immunoprecipitation
(15-25 μg/ml), and immunohistochemistry (15-25 μg/ml).
Background TIA-1 and TIAR are two closely related proteins that are thought to function as mediators of apoptotic cell death. TIA-1 is found in the granules of cytotoxic lymphocytes, whereas TIAR expression is limited to the nucleus and found in a much broader range of cells including, but not limited to, cells of hematopoietic origin. TIAR is translocated to the cytoplasm shortly after Fas ligation and this event immediately proceeds the onset of DNA fragmentation. A novel serine/threonine kinase that is activated as a result of Fas ligation, designated FAST (Fas-activated serine/threonine), shows kinase specificity towards both TIA-1 and TIAR.
Concentration 0.2 mg/ml
Storage Store at -20 °C. For long term storage, aliquot and freeze at -70 °C. Avoid repeated freeze/defrost cycles.

Buffer System:
Supplied in phosphate-buffered saline (PBS) containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide.
Aff - Purified
The antibody recognizes TIA-1.
Human, mouse, rat. Reactivity to other species has not been tested.

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