AP10349PU-N TLR11 antibody

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Rabbit anti Chimpanzee, Human, Monkey TLR11


Product Description for TLR11

Rabbit anti Chimpanzee, Human, Monkey TLR11.
Presentation: Aff - Purified
Product is tested for Dot blot, Enzyme Immunoassay, Western blot / Immunoblot.

Properties for TLR11

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Gm287, Toll-like receptor 11
Presentation Aff - Purified
Reactivity Chimp, Hu, Mky
Applications Dot, E, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Syntehtic peptide form unique region near the C-terminal end of Toll receptor-11 protein, this peptide sequence is not present in other members of the TLR family.
The peptide was post-synthetically modified to achieve desired antigenicity.
Application ELISA/Dot blot: 1/20,000.
Western Blot: 1/500.
Background Toll like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.
Concentration 0.56-0.72 mg/ml (lot specific)
Storage Store the antibody undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Affinity Chromatography using immobilized antigen
Buffer System:
Stabilization buffer
Liquid purified Ig fraction
Aff - Purified
Toll-like receptor 11 (TLR11)
Human, Chimpanzee and Monkey.

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