Product Description for TLR2 6x Sampler Kit
Product is tested for Enzyme Immunoassay, Functional assay, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Paraffin Sections, Western blot / Immunoblot, Flow Cytometry.
Properties for TLR2 6x Sampler Kit
|Product Category||Primary Antibodies|
|Quantity||5x25µg + 1x50µl kit|
|Synonyms||Toll-like receptor 2|
|Reactivity||Can, Chimp, Hu, Ms, Rt|
|Applications||E, F, FN, ICC/IF, IP, P, WB|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Material safety datasheet||MSDS for Polyclonal Antibodies (de)|
|Add. information||TLR2 Antibody Screening Set contains 7 Polyclonal or Monoclonal Antibodies:
SM7100P-50: TLR2 Antibody (50 µl Ascites).
SP7193P-25: TLR2 Antibody (25 µg Purified).
SM1825P-25: TLR2 Antibody (25 µg Purified).
SP7126P-25: TLR2 Antibody (25 µg Purified).
SP7127P-25: TLR2 Antibody (25 µg Purified).
SP7194P-25: TLR2 Antibody (25 µg Purified).
AM20374PU-25: TLR2 Antibody (25 µg Purified).
Western blot analysis.
|Background||The Toll-like receptor (TLR) family in mammals comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. TLR2 is differentially expressed in human cells. TLR2 is expressed in tonsils, lymph nodes, and appendices, activated B-cells in germinal centers. CD14+ monocytes expressed the highest level of TLR2 followed by CD15+ granulocytes, and CD19+ B-cells, CD3+ T-cells, and CD56+ NK cells did not express TLR2.|