NB100-56601 TLR4 antibody

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0.1 mg / €380.00

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Rat anti Mouse TLR4 MTS510


Product Description for TLR4

Rat anti Mouse TLR4 MTS510.
Product is tested for Immunoprecipitation, Flow Cytometry.

Properties for TLR4

Product Category Primary Antibodies
Quantity 0.1 mg
Reactivity Ms
Applications F, IP
Clonality Monoclonal
Clone MTS510
Host Rat
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

This antibody was developed by immunizing rats with the Ba/F3 cell line expressing mouse TLR4 and MD-2 (7).
Background The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). Ten human homologs of TLRs (TLR1-10) have been described (3). Among this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TLR2 and TLR4 may serve as potential main mediators of LPS signaling (4,5). The TLR4 cDNA codes for a protein consisting of 799 amino acids with approximate molecular weight of 88 kDa (6).
Buffer System:
PBS. Filter sterilized. Sodium azide free.
Mouse Not yet tested in other species.

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