TA320074 TMEM88 / TMEM88A (C-term) antibody

Rabbit Polyclonal TMEM88 Antibody

See related secondary antibodies

Search for all "TMEM88 / TMEM88A"

0.1 mg / €371.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat TMEM88 / TMEM88A

TA320074

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  • TA320074

Product Description for TMEM88 / TMEM88A

Rabbit anti Human, Mouse, Rat TMEM88 / TMEM88A.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for TMEM88 / TMEM88A

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms Transmembrane protein 88
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q6PEY1
Immunogen:
19 amino acid peptide near the carboxy terminus of human TMEM88
GeneID:
92162
Property C-term
Application ELISA.
Western blot: 1-2 µg/ml.
Positive control: Human Brain Tissue Lysate.
Background Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.
General Readings
  1. Lee HJ, Finkelstein D, Li X, Wu D, Shi DL, Zheng JJ. Identification of transmembrane protein 88 (TMEM88) as a dishevelled-binding protein. J Biol Chem. 2010 Dec 31;285(53):41549-56. doi: 10.1074/jbc.M110.193383. Epub 2010 Nov 2. PubMed PMID: 21044957. (Free PMC Article available, 7 images available)
Storage Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography purified via peptide column
Buffer System:
PBS containing 0.02% sodium azide
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, mouse, rat
Specificity
Specificity:
This antibody detects TMEM88 / TMEM88A at C-term.

Accessory Products

Proteins and/or Positive Controls

Proteins for TMEM88 / TMEM88A (3 products)

Catalog No. Species Pres. Purity   Source  

TMEM88 / TMEM88A

TMEM88 / TMEM88A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

TMEM88 / TMEM88A

TMEM88 / TMEM88A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

TMEM88 / TMEM88A

TMEM88 / TMEM88A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Positive controls for TMEM88 / TMEM88A (1 products)

Catalog No. Species Pres. Purity   Source  

TMEM88 overexpression lysate

TMEM88 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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