TA802384 TOP2A antibody

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0.1 ml / €325.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Mouse anti Human TOP2A OTI2A9

TA802384

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Product Description for TOP2A

Mouse anti Human TOP2A OTI2A9.
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for TOP2A

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms DNA topoisomerase 2-alpha, DNA topoisomerase II alpha isozyme, TOP2, Top-2
Presentation Purified
Reactivity Hu
Applications P, WB
Clonality Monoclonal
Clone OTI2A9
Host Mouse
Isotype IgG2b
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P11388
Immunogen:
Human recombinant protein fragment corresponding to amino acids 1100-1531 of human TOP2A(NP_001058) produced in E.coli.
GeneID:
7153
Isotype control AM03110PU-N, SM12P
Application WB 1:2000
IHC 1:150
Background This gene encodes a D topoisomerase, an enzyme that controls and alters the topologic states of D during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsiol stress that occurs during D transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex D which allows the strands to pass through one another, thus altering the topology of D. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. [provided by RefSeq, Jul
Format
Purification:
Purified from mouse ascites fluids by affinity chromatography
Buffer System:
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for TOP2A (2 products)

Catalog No. Species Pres. Purity   Source  

TOP2A

TOP2A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TOP2A

TOP2A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Positive controls for TOP2A (1 products)

Catalog No. Species Pres. Purity   Source  

TOP2A overexpression lysate

TOP2A overexpression lysate
0.1 mg / €480.00
  OriGene Technologies, Inc.
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