discontinued

NB100-304 TP53BP1 antibody

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0.1 ml / €400.00

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Rabbit anti Human, Mouse TP53BP1

NB100-304

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Product Description for TP53BP1

Rabbit anti Human, Mouse TP53BP1.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot, Flow Cytometry.

Properties for TP53BP1

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms 53BP1, Tumor suppressor p53-binding protein 1, p53-binding protein 1, p53BP1
Presentation Aff - Purified
Reactivity Hu, Ms
Applications F, ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q12888
Immunogen:
The epitope recognized by this antibody maps to a region between residues 350 and 400 of human tumor protein p53 binding protein 1 using the numbering given in entry NP_005648.1 (GeneID 7158).
GeneID:
7158
Add. information Research Areas: DNA Repair, Cancer
Application flow cytometry / FACS analysis, Immunocytochemistry, immunofluorescence, Western Blot, This antibody is useful for Western Blot, Immunocytochemistry and Flow Cytometry. Flow Cytometry: 1.5 mcg/ml in a 150 mcl reaction immunofluorescence, flow cytometry / FACS analysis, Immunocytochemistry, immunofluorescence, Western Blot
Background P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.
Concentration 1 mg/ml
General Readings
  1. Riballo, et al. Mol Cell 16(5): 715-724 (2004)
Storage Store at 4C. Do not freeze.
Format
Purification:
Affinity purified
Buffer System:
0.09% Sodium Azide
Purity:
Affinity purified
State:
Aff - Purified
Specificity
Specificity:
NB100-304 is specific for human 53BP1 protein.
Species:
Human, Mouse
Gene ID 7158

Accessory Products

Proteins and/or Positive Controls

Proteins for TP53BP1 (3 products)

Catalog No. Species Pres. Purity   Source  

TP53BP1 (transcript variant 3)

TP53BP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

TP53BP1

TP53BP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TP53BP1

TP53BP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Positive controls for TP53BP1 (1 products)

Catalog No. Species Pres. Purity   Source  

TP53BP1 overexpression lysate

TP53BP1 overexpression lysate
0.1 mg / €480.00
  OriGene Technologies, Inc.
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