discontinued

NB100-304 TP53BP1 antibody

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Rabbit anti Human, Mouse TP53BP1

NB100-304

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Product Description for TP53BP1

Rabbit anti Human, Mouse TP53BP1.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot, Flow Cytometry.

Properties for TP53BP1

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms 53BP1, Tumor suppressor p53-binding protein 1, p53-binding protein 1, p53BP1
Presentation Aff - Purified
Reactivity Hu, Ms
Applications F, ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q12888
Immunogen:
The epitope recognized by this antibody maps to a region between residues 350 and 400 of human tumor protein p53 binding protein 1 using the numbering given in entry NP_005648.1 (GeneID 7158).
GeneID:
7158
Add. information Research Areas: DNA Repair, Cancer
Application flow cytometry / FACS analysis, Immunocytochemistry, immunofluorescence, Western Blot, This antibody is useful for Western Blot, Immunocytochemistry and Flow Cytometry. Flow Cytometry: 1.5 mcg/ml in a 150 mcl reaction immunofluorescence, flow cytometry / FACS analysis, Immunocytochemistry, immunofluorescence, Western Blot
Background P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.
Concentration 1 mg/ml
General Readings
  1. Riballo, et al. Mol Cell 16(5): 715-724 (2004)
Storage Store at 4C. Do not freeze.
Format
Purification:
Affinity purified
Buffer System:
0.09% Sodium Azide
Purity:
Affinity purified
State:
Aff - Purified
Specificity
Specificity:
NB100-304 is specific for human 53BP1 protein.
Species:
Human, Mouse
Gene ID 7158

Accessory Products

Proteins and/or Positive Controls

Proteins for TP53BP1 (3 products)

Catalog No. Species Pres. Purity   Source  

TP53BP1 (transcript variant 3)

TP53BP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

TP53BP1

TP53BP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

TP53BP1

TP53BP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for TP53BP1 (1 products)

Catalog No. Species Pres. Purity   Source  

TP53BP1 overexpression lysate

TP53BP1 overexpression lysate
0.1 mg / €480.00
  OriGene Technologies, Inc.
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