discontinued

NB100-904 TP53BP1 (Cocktail) antibody

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Rabbit anti Human, Mouse TP53BP1

NB100-904

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  • NB100-904
  • NB100-904

Product Description for TP53BP1

Rabbit anti Human, Mouse TP53BP1.
Properties: (Cocktail)
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.

Properties for TP53BP1

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms 53BP1, Tumor suppressor p53-binding protein 1, p53-binding protein 1, p53BP1
Presentation Aff - Purified
Reactivity Hu, Ms
Applications ICC/IF, P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q12888
Immunogen:
A synthetic peptide, which represented a portion of human tumor protein p53-binding protein 1 encoded in exon 11, 12 and 19 (LocusLink ID 7158). This antibody is a cocktail hybrid of NB 100-304 and NB 100-305.
GeneID:
7158
Property Cocktail
Add. information Research Areas: Cancer, DNA Repair
Application Immunocytochemistry, Western Blot, NB 100-904 is useful for Western Blot where a band at ~220 kD is seen on SDS-PAGE. It may also be used for immunocytochemistry. Irradiated lysates demonstrate a gel shift. This antibody has not yet been tested in immunoprecipitation., Western Blot 1:1,000 - 1:10,000 (ECL), Immunocytochemistry 1:100 - 1:1,000
Background P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.
Concentration 1 mg/ml
General Readings
  1. Yanagawa T, Funasaka T, Tsutsumi S, Hu H, Watanabe H, Raz A. Regulation of phosphoglucose isomerase/autocrine motility factor activities by the poly(ADP-ribose) polymerase family-14. Cancer Res. 2007 Sep 15;67(18):8682-9. PubMed PMID: 17875708.
Storage Store at 4C. Do not freeze.
Format
Purification:
Affinity purified
Buffer System:
0.1% Sodium Azide
Purity:
Affinity purified
State:
Aff - Purified
Specificity
Specificity:
NB100-904 is specific for human 53BP1 protein.
Species:
Human, Mouse
Gene ID 7158

Accessory Products

Proteins and/or Positive Controls

Proteins for TP53BP1 (3 products)

Catalog No. Species Pres. Purity   Source  

TP53BP1 (transcript variant 3)

TP53BP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

TP53BP1

TP53BP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

TP53BP1

TP53BP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for TP53BP1 (1 products)

Catalog No. Species Pres. Purity   Source  

TP53BP1 overexpression lysate

TP53BP1 overexpression lysate
0.1 mg / €480.00
  OriGene Technologies, Inc.
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