NBP1-49288 TPMT antibody

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Rabbit anti Human TPMT

Product Description for TPMT

Rabbit anti Human TPMT.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for TPMT

Product Category Primary Antibodies
Quantity 0.2 mg
Synonyms anti-HGNC:12014antibody, anti-S-adenosyl-L-methionine:thiopurine S-methyltr, anti-TPMT antibody, anti-thiopurine S-methyltransferaseantibody, anti-thiopurine methyltransferase antibody
Presentation Aff - Purified
Reactivity Hu
Applications E, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Swiss Prot Num:
Synthetic peptide (KLH-coupled) within residues 200-250 of human TPMT protein (Swiss Prot: P51580)
Background This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
Concentration 0.5 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Immunogen affinity purified
Buffer System:
PBS, pH 7.4
Aff - Purified
Gene ID 7172

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