AP54347PU-N TPSAB1 (C-term) antibody

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0.4 ml / €370.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human, Mouse TPSAB1

Product Description for TPSAB1

Rabbit anti Human, Mouse TPSAB1.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for TPSAB1

Product Category Primary Antibodies
Quantity 0.4 ml
Synonyms TPS1, TPS2, TPSB1, Tryptase alpha-1
Presentation Aff - Purified
Reactivity Hu, Ms
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Swiss Prot Num:
KLH conjugated synthetic peptide between 248-275 amino acids from the C-terminal region of human TPSAB1
Property C-term
Add. information Molecular Weight: 30773 Da
Application ELISA: 1:1;000.
Western blot: 1:100~500.
Background Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
Concentration lot specific
General Readings
  1. Lee, J.W., et al. Dig. Dis. Sci. 55(10):2922-2928(2010).
  2. Trivedi, N.N., et al. J. Allergy Clin. Immunol. 124(5):1099-1105(2009).
  3. Radhakrishnan, Y., et al. Biol. Reprod. 81(4):647-656(2009).
  4. Schiemann, F., et al. J. Immunol. 183(4):2223-2231(2009).
  5. Wei, Z.Y., et al. Fa Yi Xue Za Zhi 25(3):164-167(2009).
Storage Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Protein A column followed by peptide affinity purification
Buffer System:
PBS with 0.09% (W/V) sodium azide
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, mouse
This antibody detects TPSAB1 (C-term).

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