AP54348PU-N TPSD1 (C-term) antibody

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0.4 ml / €370.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human TPSD1

AP54348PU-N

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  • AP54348PU-N

Product Description for TPSD1

Rabbit anti Human TPSD1.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for TPSD1

Product Category Primary Antibodies
Quantity 0.4 ml
Synonyms Tryptase delta
Presentation Aff - Purified
Reactivity Hu
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9BZJ3
Immunogen:
KLH conjugated synthetic peptide between 171-201 amino acids from the C-terminal region of human TPSD1
GeneID:
23430
Property C-term
Add. information Molecular Weight: 26584 Da
Application ELISA: 1:1;000.
Western blot: 1:100~500.
Immunohistochemistry on paraffin sections: 1:50~100.
Background Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. TPSD1 was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein.
Concentration lot specific
General Readings
  1. Jackson, N.E., et al. J. Biol. Chem. 283(49):34178-34187(2008).
  2. Caughey, G.H. J. Allergy Clin. Immunol. 117(6):1411-1414(2006).
  3. Wang, H.W., et al. J. Immunol. 169(9):5145-5152(2002).
  4. Caughey, G.H. Mol. Immunol. 38 (16-18), 1353-1357 (2002).
  5. Soto, D., et al. Clin. Exp. Allergy 32(7):1000-1006(2002).
Storage Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein A column followed by peptide affinity purification
Buffer System:
PBS with 0.09% (W/V) sodium azide
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human
Specificity
Specificity:
This antibody detects TPSD1 (C-term).
Gene ID 23430

Accessory Products

Proteins and/or Positive Controls

Positive controls for TPSD1 (1 products)

Catalog No. Species Pres. Purity   Source  

TPSD1 overexpression lysate

TPSD1 overexpression lysate
0.1 mg / €280.00
  OriGene Technologies, Inc.
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