discontinued

AM05313PU-N Trefoil factor 1 / pS2 antibody

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Mouse anti Human Trefoil factor 1 / pS2 pS2.1

Product Description for Trefoil factor 1 / pS2

Mouse anti Human Trefoil factor 1 / pS2 pS2.1.
Presentation: Purified
Product is tested for Paraffin Sections.

Properties for Trefoil factor 1 / pS2

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms BCEI, Breast cancer estrogen-inducible protein, PNR-2, Polypeptide P1.A, TFF1
Presentation Purified
Reactivity Hu
Applications P
Clonality Monoclonal
Clone pS2.1
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P04155
Immunogen:
Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with synthetic peptide of 31 amino acids from the C-terminus of human pS2 protein and mouse myeloma p3-NS1-Ag4-1 cells.
GeneID:
7031
Isotype control AM03095PU-N, SM10P (for use in human samples)
Application This antibody can be used for Immunohistochemistry on Frozen and Formalin/paraffin embedded tissues at 2-4 µg/ml.
Positive Control: Breast carcinomas.
Background Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.
Concentration Lot specific
General Readings
  1. Masiakowski P, Breathnach R, Bloch J, Gannon F, Krust A, Chambon P. Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line. Nucleic Acids Res. 1982 Dec 20;10(24):7895-903. PubMed PMID: 6897676. (Free PMC Article available)
  2. Jeltsh JM, et al. Structure of human oestrogen-responsive gene pS2. Nucleic Acids Res 15:1401-1414, 1987.
  3. Mori K, et al. Complete primary structure of the oestrogen-responsive gene (pS2) product. J Biochem 107:73-76, 1990
  4. Rio MC, Bellocq JP, Daniel JY, Tomasetto C, Lathe R, Chenard MP, et al. Breast cancer-associated pS2 protein: synthesis and secretion by normal stomach mucosa. Science. 1988 Aug 5;241(4866):705-8. PubMed PMID: 3041593.
  5. Rio MC, Bellocq JP, Gairard B, Rasmussen UB, Krust A, Koehl C, et al. Specific expression of the pS2 gene in subclasses of breast cancers in comparison with expression of the estrogen and progesterone receptors and the oncogene ERBB2. Proc Natl Acad Sci U S A. 1987 Dec;84(24):9243-7. PubMed PMID: 3321071. (Free PMC Article available)
  6. Molina R, et al. Estrogen-inducible pS2 protein: Tumor characteristics and clinical behavior in breast cancer. Proc Endocrine Soc 61(#148), 1990.
  7. Abbondanzo SL, et. al. Prognostic significance of immuno-cytochemically determined pS2 in axillary node-negative breast carcinoma. Breast Cancer Res Treat 16:182, 1990.
Storage Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Format
Buffer System:
PBS containing 0.08% Sodium Azide as preservative.
Purity:
Purified
State:
Liquid purified IgG fraction.
Purified
Specificity
Specificity:
It recognizes a polypeptide of 6.5 kDa which is identified as pS2 estrogen-regulated protein.
Species:
Human.
Gene ID 7031

Accessory Products

Proteins and/or Positive Controls

Proteins for Trefoil factor 1 / pS2 (13 products)

Catalog No. Species Pres. Purity   Source  

Trefoil factor 1 / pS2

Trefoil factor 1 / pS2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.

Trefoil factor 1 / pS2

Trefoil factor 1 / pS2 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
20 µg / €230.00
  OriGene Technologies, Inc.

Trefoil factor 1 / pS2

Trefoil factor 1 / pS2 Human Purified > 97.0% as determined by: 
(a) Analysis by RP-HPLC. 
(b) Analysis by SDS-PAGE.
E. coli
  OriGene Technologies GmbH

Trefoil factor 1 / pS2

Trefoil factor 1 / pS2 Human Purified > 97.0% as determined by: 
(a) Analysis by RP-HPLC. 
(b) Analysis by SDS-PAGE.
E. coli
  OriGene Technologies GmbH

Trefoil factor 1 / pS2

Trefoil factor 1 / pS2 Human Purified > 97.0% as determined by: 
(a) Analysis by RP-HPLC. 
(b) Analysis by SDS-PAGE.
E. coli
  OriGene Technologies GmbH

Trefoil factor 1 / pS2 (His-tagged)

Trefoil factor 1 / pS2 Human Purified > 95.0% as determined by SDS-PAGE. E. coli
  OriGene Technologies GmbH

Trefoil factor 1 / pS2 (His-tagged)

Trefoil factor 1 / pS2 Human Purified > 95.0% as determined by SDS-PAGE. E. coli
  OriGene Technologies GmbH

Trefoil factor 1 / pS2 (His-tagged)

Trefoil factor 1 / pS2 Human Purified > 95.0% as determined by SDS-PAGE. E. coli
  OriGene Technologies GmbH

Trefoil factor 1 / pS2 (25-84, His-tag)

Trefoil factor 1 / pS2 Human Purified > 90 % E. coli
0.25 mg / €1,070.00
  OriGene Technologies GmbH

Trefoil factor 1 / pS2 (25-84, His-tag)

Trefoil factor 1 / pS2 Human Purified > 90 % E. coli
50 µg / €400.00
  OriGene Technologies GmbH

Trefoil factor 1 / pS2

Trefoil factor 1 / pS2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Trefoil factor 1 / pS2

Trefoil factor 1 / pS2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Trefoil factor 1 / pS2

Trefoil factor 1 / pS2 Human
  Abnova Taiwan Corp.

Positive controls for Trefoil factor 1 / pS2 (2 products)

Catalog No. Species Pres. Purity   Source  

Estrogen Inducible Protein pS2 Lysate

Western Blot: Estrogen Inducible Protein pS2 Lysate [NBL1-16839] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for TFF1
  Novus Biologicals Inc.

TFF1 overexpression lysate

TFF1 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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