NBP1-22514 Trem1 (RM0138-3C66) antibody

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Rat anti Mouse Trem1 (RM0138-3C66) RM0138-3C66


Product Description for Trem1 (RM0138-3C66)

Rat anti Mouse Trem1 (RM0138-3C66) RM0138-3C66.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for Trem1 (RM0138-3C66)

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms anti-TREM 1 antibody, anti-Triggering receptor TREM1 antibody, anti-Triggering receptor expressed on monocytes 1, anti-triggering receptor expressed on myeloid cell
Presentation Purified
Reactivity Ms
Applications WB
Clonality Monoclonal
Clone RM0138-3C66
Host Rat
Isotype IgG2
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Mouse recombinant protein of the extracellular domain of TREM-1
Application Western Blot, This antibody detects mouse of TREM-1, but not TREM-2b in Western blotting., Western Blot 1:500-1:1000
Background TREM1 is also known as triggering receptor expressed on myeloid cells 1, and triggering receptor expressed on monocytes 1. TREM1 is a Type I membrane protein that contains an immunoglobulin-like V-type domain. An alternatively spliced protein variant may be secreted. TREM1 is highly expressed on peripheral blood myeloid cells (particularly mature monocytes and granulocytes); TREM1 expression can be further upregulated by bacteria, fungi and lipopolysaccharide. TREM1 has been shown to interact with the adaptor protein DAP12 to stimulate neutrophil and monocyte-mediated inflammatory responses through the triggering and release of pro-inflammatory cytokines and chemokines. TREM1 is thought to amplify inflammatory responses to fungal and bacterial infections and potentiate septic shock.
Storage Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
protein G purified
Buffer System:
No Preservative
protein G purified
This was produced from a hybridoma (mouse myeloma) fused with spleen cells from a rat immunized with mouse recombinant protein of the EC-domain of TREM-1.

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