TA311600 TREML1 (C-term) antibody

Goat Anti-TREML1 Antibody

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0.1 mg / €325.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Goat anti Human TREML1

Product Description for TREML1

Goat anti Human TREML1.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for TREML1

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms TLT-1, TLT1, Trem-like transcript 1 protein, Triggering receptor expressed on myeloid cells-like protein 1
Presentation Aff - Purified
Reactivity Hu
Applications E, WB
Clonality Polyclonal
Host Goat
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q86YW5
Immunogen:
Peptide from the C-Terminus of the protein sequence according to NP_835468.1.
AA Sequence:
CGPAQNPPNNQTPS
GeneID:
340205
Property C-term
Application Peptide ELISA: Antibody detection limit dilution 1:2000.
Western blot: 0.3-1µg/ml. Approx 30kDa band observed in Human Bone Marrow lysates (calculated MW of 32.7kDa according to NP_835468.1).
Background The TREMs (triggering receptors expressed on myeloid cells) represent a family of 5 receptors clustered on murine chromosome 17. TREM-like transcript-1 (TLT-1) was initially characterized as the putative inhibitory receptor within the TREM locus on chromosome 6 and was suggested to play a critical role in modulating TREM-associated immunity. It may also play a significant role in maintaining vascular hemostasis, coagulation, and inflammation at sites of injury through its location in platelets.
TREML1 is the first ITIM-containing receptor carrying a potential Src homology 3 domain ligand. TREML1 transcripts are abundant in bone marrow cells, but not in lymphocytes, and phosphorylated TREML1 associates with SHP-1, suggesting that it is indeed an inhibitory receptor.
Concentration 0.5 mg/ml
General Readings Nurden AT, Nurden P, Bermejo E, Combrié R, McVicar DW, Washington AV.
Phenotypic heterogeneity in the Gray platelet syndrome extends to the expression of TREM family member, TLT-1.
Thrombosis and haemostasis 2008 Jul 100 (1): 45-51.
PMID: 18612537
Storage Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
Buffer System:
Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human
Specificity
Specificity:
This antibody detects TREML1 at C-term.

Accessory Products

Proteins and/or Positive Controls

Proteins for TREML1 (3 products)

Catalog No. Species Pres. Purity   Source  

TREML1

TREML1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

TREML1

TREML1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €399.00
  OriGene Technologies, Inc.

TREML1

TREML1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

Positive controls for TREML1 (2 products)

Catalog No. Species Pres. Purity   Source  

TREML1 Lysate

Western Blot: TREML1 Lysate [NBL1-17265] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for TREML1
  Novus Biologicals Inc.

TREML1 overexpression lysate

TREML1 overexpression lysate
0.1 mg / €280.00
  OriGene Technologies, Inc.
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