NBP1-01042 TRHR1 antibody

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Rabbit anti Human, Mouse, Rat TRHR1

Product Description for TRHR1

Rabbit anti Human, Mouse, Rat TRHR1.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for TRHR1

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms TRH-R, Thyroliberin receptor 1, Thyrotropin-releasing hormone receptor
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Application ELISA, Western Blot, Western blot analysis of TRH-R1 (W234) antibody in extracts from COS7 cells. Detects a band at molecular weight: 50kDa, ELISA 1:20000-1:40000, Western Blot 1:500-1:1000,
Background Thyrotrophin-releasing hormone (TRH) is a hypothalamic tripeptide that stimulates, via its receptor in the anterior pituitary gland, the release of thyrotrophin (TSH) and prolactin. The TRH receptors, TRH-R1 and TRH-R2, are G protein-coupled proteins containing seven transmembrane domains and other conserved regions. In rat, two isoforms exist, TRH-R (412) and TRH-R (387), that differ at their carboxy termini. TRH receptors are distributed throughout the central and peripheral nervous systems and are present in a variety of tissues. TRH-R2 displays 50% homology to TRH-R1 and is more restricted to the central nervous system than TRH-R1. Mutation in the TRH receptor gene is associated with isolated central hypothyroidism, a rare disorder characterized by insufficient TSH secretion resulting in low levels of thyroid hormones.
Concentration 1 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Immunogen affinity purified
Buffer System:
15mM Sodium Azide
Immunogen affinity purified
Aff - Purified
TRH-R1 (W234) detects endogenous levels of TRH-R1 protein.
Human, Mouse, Rat

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