AP31074PU-N TRIM2 / RNF86 (758-771) antibody

See related secondary antibodies

Search for all "TRIM2 / RNF86"

50 µg / €380.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Goat anti Bat, Bovine, Canine, Chicken, Equine, Hamster, Human, Monkey, Mouse, Rabbit, Rat, Xenopus, Zebrafish TRIM2 / RNF86

AP31074PU-N

More Views

  • AP31074PU-N

Product Description for TRIM2 / RNF86

Goat anti Bat, Bovine, Canine, Chicken, Equine, Hamster, Human, Monkey, Mouse, Rabbit, Rat, Xenopus, Zebrafish TRIM2 / RNF86.
Properties: (758-771)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for TRIM2 / RNF86

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms KIAA0517, RING finger protein 86, Tripartite motif-containing protein 2
Presentation Aff - Purified
Reactivity Bov, Bt, Can, Chk, Elephant, Eq, Hst, Hu, Mky, Ms, Platypus, Rb, Rt, Xen, Ze
Applications E, P, WB
Clonality Polyclonal
Host Goat
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9C040
Immunogen:
Synthetic peptide from the C-terminus of human TRIM2 / RNF86 (NP_056086.2; NP_001123539.1)
AA Sequence:
DSGNHCFKVYRYLQ
GeneID:
23321
Remarks:
Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Opossum, Turkey, Chicken, Platypus, Lizard, Xenopus, Stickleback, Pufferfish, Zebrafish (100%); Pig (86%)
Property 758-771
Add. information Calculated Molecular Weight: 81.5 kDa (Human NP_001123539.1), 84.4 KDa (Human NP_056086.2) and 83.3 kDa (Rat NP_001102022.1).
Application ELISA: 1/16000.
Immunohistochemistry on Paraffin Sections: 6.25 µg/ml.
Western Blot: 0.5 - 2 µg/ml.
Background KIAA0517 / TRIM2 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants.
Concentration 0.5 mg/ml
Storage Store the antibody (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Immunoaffinity Chromatography
Buffer System:
Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% Sodium Azide as preservative
State:
Liquid purified IgG fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Opossum, Turkey, Chicken, Platypus, Lizard, Xenopus, Stickleback, Pufferfish, Zebrafish, Pig
Specificity
Specificity:
Recognizes Tripartite Motif Protein TRIM2 at aa 758-771.
It is expected to recognise both reported isoforms (NP_056086.2; NP_001123539.1).
Cross-reactivity with TRIM3 has been demonstrated.
Gene ID 23321

Accessory Products

Proteins and/or Positive Controls

Positive controls for TRIM2 / RNF86 (2 products)

Catalog No. Species Pres. Purity   Source  

TRIM2 Lysate

Western Blot: TRIM2 Lysate [NBL1-17280] - Western Blot experiments. Left-Control; Right -Over-expression Lysate
  Novus Biologicals Inc.

TRIM2 overexpression lysate

TRIM2 overexpression lysate
0.1 mg / €495.00
  OriGene Technologies, Inc.
  • LinkedIn