Product Description for Tropomyosin-1 (TPM1)
Rabbit anti Canine, Human, Mouse, Rat, Zebrafish, African clawed frog Tropomyosin-1 (TPM1).
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.
Properties for Tropomyosin-1 (TPM1)
Product Category | Primary Antibodies |
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Target Category | |
Quantity | 0.1 mg |
Synonyms | Alpha-tropomyosin, C15orf13, TMSA, Tropomyosin alpha-1 chain |
Presentation | Aff - Purified |
Reactivity | African clawed frog, Can, Hu, Ms, Rt, Ze |
Applications | P, WB |
Clonality | Polyclonal |
Host | Rabbit |
Shipping to | Europe only |
PDF datasheet | View Datasheet |
Manufacturer | AVIVA Systems Biology |
Datasheet Extract
Immunogen |
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Add. information | Rabbit IgG purified by protein A chromatography. 31kDa, 33kDa, 33kDa, 33kDa |
Application | Suggested dilution at 1.25 ELISA titre using peptide based assay: 1:312500 |
Background | TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. |
General Readings | Lin,J.C. (2005) Mol. Cell. Biol. 25 (22), 10111-10121 |
Storage | Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 ul of distilled water. Final antibody concentration is 2 mg/ml. For longer periods of storage, store at -20DegC. Avoid repeat freeze-thaw cycles. |
Format |
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Specificity |
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Gene ID | 7168 |
Accessory Products
Proteins and/or Positive Controls
Proteins for Tropomyosin-1 (TPM1) (15 products)
Catalog No. | Species | Pres. | Purity | Source | |||
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TP301262 |
Tropomyosin-1 (TPM1) (transcript variant 5) |
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Human |
> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
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OriGene Technologies, Inc. | |||||||
TP318007 |
Tropomyosin-1 (TPM1) (transcript variant 1) |
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Human |
> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
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OriGene Technologies, Inc. | |||||||
TP318995 |
Tropomyosin-1 (TPM1) (transcript variant 7) |
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Human |
> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|||
OriGene Technologies, Inc. | |||||||
TP319543 |
Tropomyosin-1 (TPM1) (transcript variant 3) |
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Human |
> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|||
OriGene Technologies, Inc. | |||||||
TP319606 |
Tropomyosin-1 (TPM1) (transcript variant 4) |
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Human |
> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|||
OriGene Technologies, Inc. | |||||||
TP319652 |
Tropomyosin-1 (TPM1) (transcript variant 2) |
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Human |
> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|||
OriGene Technologies, Inc. | |||||||
TP720234 |
Tropomyosin-1 (TPM1) (transcript variant 5) |
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Human |
> 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining. |
E. coli |
10 µg /
€299.00
|
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OriGene Technologies, Inc. | |||||||
AR09621PU-L |
Tropomyosin-1 (TPM1) (1-284, His-tag) |
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Human | Purified | > 90 % by SDS - PAGE | E. coli |
0.5 mg /
€820.00
|
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OriGene Technologies GmbH | |||||||
AR09621PU-N |
Tropomyosin-1 (TPM1) (1-284, His-tag) |
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Human | Purified | > 90 % by SDS - PAGE | E. coli |
0.1 mg /
€320.00
|
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OriGene Technologies GmbH | |||||||
H00007168-P01-10 |
Tropomyosin-1 (TPM1) |
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Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. | ||||
Abnova Taiwan Corp. | |||||||
H00007168-P01-25 |
Tropomyosin-1 (TPM1) |
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Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. | ||||
Abnova Taiwan Corp. | |||||||
H00007168-Q01-10 |
Tropomyosin-1 (TPM1) |
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Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. | ||||
Abnova Taiwan Corp. | |||||||
H00007168-Q01-25 |
Tropomyosin-1 (TPM1) |
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Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. | ||||
Abnova Taiwan Corp. | |||||||
NBP1-48329-0.1 |
Tropomyosin-1 (TPM1) |
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Human | Purified | |||||
Novus Biologicals Inc. | |||||||
NBP1-48329-0.5 |
Tropomyosin-1 (TPM1) |
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Human | Purified | |||||
Novus Biologicals Inc. |
Positive controls for Tropomyosin-1 (TPM1) (1 products)
Catalog No. | Species | Pres. | Purity | Source | |||
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NBL1-17219 |
Tropomyosin-1 Lysate |
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Novus Biologicals Inc. |
Recommended Secondary Antibodies for Tropomyosin-1 (TPM1) (9 products)
Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
---|---|---|---|---|---|---|---|
R1364AP |
Rabbit IgG (H+L chain) antibody |
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Goat | AP | Rb | E, WB | |||
OriGene Technologies GmbH | |||||||
R1364B |
Rabbit IgG (H+L chain) antibody |
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Goat | Biotin | Rb | E, WB | |||
OriGene Technologies GmbH | |||||||
R1364F |
Rabbit IgG (H+L chain) antibody |
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Goat | FITC | Rb | E, ICC/IF, WB | |||
OriGene Technologies GmbH | |||||||
R1364HRP |
Rabbit IgG (H+L chain) antibody |
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Goat | HRP | Rb | E, P, WB | |||
OriGene Technologies GmbH | |||||||
R1364T |
Rabbit IgG (H+L chain) antibody |
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Goat | TRITC | Rb | E, F, ICC/IF | |||
OriGene Technologies GmbH | |||||||
R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
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Donkey | PE | Rb | F | |||
OriGene Technologies GmbH | |||||||
R1458C2 |
Rabbit IgG (H+L chain, adsorbed) antibody |
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Goat | Cy2 | |||||
OriGene Technologies GmbH | |||||||
R1458C3 |
Rabbit IgG (H+L chain, adsorbed) antibody |
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Goat | Cy3 | |||||
OriGene Technologies GmbH | |||||||
R1458C5 |
Rabbit IgG (H+L chain, adsorbed) antibody |
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Goat | Cy5 | |||||
OriGene Technologies GmbH |