TA306347 TRPC3 / TRP3 (N-term) antibody

Rabbit Polyclonal TRPC3 Antibody

See related secondary antibodies

Search for all "TRPC3 / TRP3"

0.1 mg / €415.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse TRPC3 / TRP3

TA306347

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  • TA306347

Product Description for TRPC3 / TRP3

Rabbit anti Human, Mouse TRPC3 / TRP3.
Properties: (N-term)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for TRPC3 / TRP3

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms Short transient receptor potential channel 3, TRP-3, Transient receptor protein 3
Presentation Aff - Purified
Reactivity Hu, Ms
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q13507
Immunogen:
TRPC3 antibody was raised against a 14 amino acid peptide from near the amino terminus of human TRPC3.
GeneID:
7222
Property N-term
Add. information Blocking peptide available: AP30954CP-N
Application ELISA.
Western blot: 1.0 – 2.0 μg/ml
Immunohistochemistry on paraffin sections: 10.0 μg/ml
Background The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the “canonical TRP” (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors (2). TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.
Concentration 1 mg/ml
General Readings
  1. Montell C, Birnbaumer L, Flockerzi V, Bindels RJ, Bruford EA, Caterina MJ, et al. A unified nomenclature for the superfamily of TRP cation channels. Mol Cell. 2002 Feb;9(2):229-31. PubMed PMID: 11864597.
  2. Trebak M, Vazquez G, Bird GSJ, et al. The TRPC3/6/7 subfamily of cation channels. Cell Calcium 2003; 33:451-61.
  3. Zitt C, Obukhov AG, Strübing C, Zobel A, Kalkbrenner F, Lückhoff A, et al. Expression of TRPC3 in Chinese hamster ovary cells results in calcium-activated cation currents not related to store depletion. J Cell Biol. 1997 Sep 22;138(6):1333-41. PubMed PMID: 9298988. (Free PMC Article available, 10 images available)
Storage Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Peptide affinity chromatography
Buffer System:
PBS containing 0.02% sodium azide
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, mouse
Specificity
Specificity:
This antibody detects TRPC3 / TRP3 at N-term.

Accessory Products

Proteins and/or Positive Controls

Proteins for TRPC3 / TRP3 (3 products)

Catalog No. Species Pres. Purity   Source  

TRPC3 / TRP3 (transcript variant 2)

TRPC3 / TRP3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.

TRPC3 / TRP3

TRPC3 / TRP3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

TRPC3 / TRP3

TRPC3 / TRP3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Positive controls for TRPC3 / TRP3 (2 products)

Catalog No. Species Pres. Purity   Source  

TRPC3 Lysate

Western Blot: TRPC3 Lysate [NBL1-17331] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for TRPC3.
  Novus Biologicals Inc.

TRPC3 overexpression lysate

TRPC3 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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