discontinued

NB100-98906 TRPV4 antibody

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0.1 ml / €360.00

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Rabbit anti Chicken TRPV4

NB100-98906

Product Description for TRPV4

Rabbit anti Chicken TRPV4.
Presentation: Serum
Product is tested for Frozen Sections, Paraffin Sections, Western blot / Immunoblot.

Properties for TRPV4

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms anti-OTRP C4 antibody, anti-OTRPC4 antibody, anti-Osm-9-like TRP channel 4 antibody, anti-TRP12 antibody, anti-Transient receptor potential cation channel s, anti-VR-OAC antibody, anti-VRL 2 antibody, anti-VRL-2 antibody, anti-VROAC antibody, anti-Vanilloid receptor-like channel 2 antibody, anti-Vanilloid receptor-like protein 2 antibody, anti-Vrl2 antibody, anti-transient receptor potential protein 12 antib, anti-vanilloid receptor-related osmotically-activa
Presentation Serum
Reactivity Chk
Applications C, P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
A synthetic peptide from the 1t cytoplasmic loop of chicken TRPV4 conjugated to an immunogenic carrier protein was used as the immunogen.
Add. information Reconstitute in 0.1 ml of sterile water. Centrifuge to remove any insoluble material. When reconstituting, glycerol (1:1) may be added for an additional stability.
Application immunohistochemistry, Western Blot, Immunohistochemistry and Western Blot., immunohistochemistry, Western Blot 1:300-1:3000
Background FUNCTION: Non-selective calcium permanent cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. SUBUNIT: Homotetramer. Self-associates in a isoform-specific manner. Isoforms 1/A and 5/D but not isoform 2/B, 4/C and 6/E can oligomerize. Interacts with calmodulin. Interacts with Map7 and Src family Tyr protein kinases LYN, SRC, FYN, HCK, LCK and YES. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. Note: Assembly of the putative homotetramer occurs primarily in the endoplasmic reticulum.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Whole antisera
Buffer System:
No Preservative
Purity:
Whole antisera
State:
Serum
Specificity
Specificity:
TRPV4.
Species:
Chicken

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