NB100-98912 TRPV5 antibody

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Sheep anti Rabbit TRPV5


Product Description for TRPV5

Sheep anti Rabbit TRPV5.
Presentation: Purified
Product is tested for Frozen Sections, Paraffin Sections, Western blot / Immunoblot.

Properties for TRPV5

Product Category Primary Antibodies
Quantity 0.5 mg
Synonyms anti-CaT2 antibody, anti-Calcium transport protein 2 antibody, anti-ECaC1 antibody, anti-Ecac antibody, anti-Epithelial calcium channel 1 antibody, anti-Otrpc3 antibody, anti-TRP V5 antibody, anti-TrpV5 antibody, anti-osm-9-like TRP channel 3 antibody, anti-transient receptor potential cation channel s
Presentation Purified
Reactivity Rb
Applications C, P, WB
Clonality Polyclonal
Host Sheep
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

A synthetic peptide from the 4th cytoplasmic loop of rabbit TRPV5 conjugated to an immunogenic carrier protein was used as the immunogen.
Add. information Reconstitute in 0.5 ml of sterile water. Centrifuge to remove any insoluble material. When reconstituting, glycerol (1:1) may be added for an additional stability.
Application immunohistochemistry, Western Blot, Immunohistochemistry and Western Blot., immunohistochemistry, Western Blot 10-50 ug/ml
Background This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. FUNCTION: Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating. SUBCELLULAR LOCATION: Apical cell membrane; Multi-pass membrane protein. Note=Colocalized with S100A10 and ANAX2 along the apical domain of kidney distal tubular cells. TISSUE SPECIFICITY: Expressed at high levels in kidney, small intestine and pancreas, and at lower levels in testis, prostate, placenta, brain, colon and rectum.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
IgG purified
Buffer System:
No Preservative
IgG purified

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