TA319973 TTYH1 (C-term) antibody

Rabbit Polyclonal TTYH1 Antibody

See related secondary antibodies

Search for all "TTYH1"

0.1 mg / €415.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human TTYH1

TA319973

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  • TA319973

Product Description for TTYH1

Rabbit anti Human TTYH1.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for TTYH1

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms Protein tweety homolog 1
Presentation Aff - Purified
Reactivity Hu
Applications E, ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9H313
Immunogen:
17 amino acid synthetic peptide near the carboxy terminus of Human TTYH1 (AP55417CP-N)
GeneID:
57348
Property C-term
Add. information Blocking peptide available: AP55417CP-N
Application Western blot: 1-2 μg/ml.
Positive Control: Raji cell lysate.
Immunofluorescence: Start at 5 μg/ml.
Immunocytochemistry: Start at 5 μg/ml.
Background TTYH1 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH1 is a Ca2+-independent, volume-sensitive large conductance chloride (Cl-) channel. TTYH1 is primarily expressed in neural tissue and upregulated in astrocytoma, glioma, and several other cancers. Recent experiments have shown that TTYH1 is an integral endoplasmic reticulum (ER) membrane protein involved in cell proliferation and is thought to play an essential role in embryonic cell growth, possibly through the Ca2+ storage/release process in ER membranes during early development.
Concentration 1.0 mg/ml
General Readings
  1. Campbell HD, Kamei M, Claudianos C, Woollatt E, Sutherland GR, Suzuki Y, et al. Human and mouse homologues of the Drosophila melanogaster tweety (tty) gene: a novel gene family encoding predicted transmembrane proteins. Genomics. 2000 Aug 15;68(1):89-92. PubMed PMID: 10950931.
  2. Matthews CA, Shaw JE, Hooper JA, Young IG, Crouch MF, Campbell HD. Expression and evolution of the mammalian brain gene Ttyh1. J Neurochem. 2007 Feb;100(3):693-707. Epub 2006 Nov 20. PubMed PMID: 17116230.
  3. Kumada T, Yamanaka Y, Kitano A, Shibata M, Awaya T, Kato T, et al. Ttyh1, a Ca(2+)-binding protein localized to the endoplasmic reticulum, is required for early embryonic development. Dev Dyn. 2010 Aug;239(8):2233-45. doi: 10.1002/dvdy.22348. PubMed PMID: 20568244.
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Affinity chromatography purified via peptide column
Buffer System:
PBS containing 0.02% Sodium Azide as preservative
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
TTYH1 antibody is Human specific. Multiple isoforms of TTYH1 are known to exist.

Accessory Products

Proteins and/or Positive Controls

Proteins for TTYH1 (4 products)

Catalog No. Species Pres. Purity   Source  

TTYH1

TTYH1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

TTYH1

TTYH1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

TTYH1

TTYH1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

TTYH1

TTYH1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for TTYH1 (2 products)

Catalog No. Species Pres. Purity   Source  

TTYH1 293T Cell Transient Overexpression Lysate(Denatured)

TTYH1 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

TTYH1 overexpression lysate

TTYH1 overexpression lysate
0.1 mg / €495.00
  OriGene Technologies, Inc.
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