discontinued

NB110-59931 Tyrosinase antibody

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6 ml / €350.00

Quick Overview

Mouse anti Human Tyrosinase T311

NB110-59931

Product Description for Tyrosinase

Mouse anti Human Tyrosinase T311.
Product is tested for Frozen Sections.

Properties for Tyrosinase

Product Category Primary Antibodies
Quantity 6 ml
Synonyms oculocutaneous albinism IA
Reactivity Hu
Applications C
Clonality Monoclonal
Clone T311
Host Mouse
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
BALB/C mice were injected with a recombinant tyrosinase protein.
Background Tyrosinase is a copper containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway. It is thought to catalyze the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.
A mutant allele of TYR is a common cause of autosomal recessive ocular albinism, also known as tyrosinase negative oculocutaneous albinism. This is an autosomal recessive disorder characterized by absence of pigment in hair, skin and eyes.
General Readings
  1. Chen et al. Proc Natl Acad Sci USA 92: 8125, 1995
Format
Purification:
Tissue culture supernatant
Buffer System:
PBS, Tissue Culture Supernatant. pH 7.3; Protein carrier
Purity:
Tissue culture supernatant
Specificity
Species:
This antibody is reactive against human.

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