AP06420PU-N Tyrosine 3-monooxygenase (TH) antibody

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0.1 mg / €350.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat Tyrosine 3-monooxygenase (TH)

AP06420PU-N

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  • AP06420PU-N

Product Description for Tyrosine 3-monooxygenase (TH)

Rabbit anti Human, Mouse, Rat Tyrosine 3-monooxygenase (TH).
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for Tyrosine 3-monooxygenase (TH)

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms TYH, Tyrosine 3-hydroxylase
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Molecular weight ~ 58 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P07101
Immunogen:
Synthetic peptide, corresponding to the N-terminus of Human TH.
GeneID:
7054
Application Western blot: 1/500-1/1000.
Immunohistochemistry on paraffin sections: 1/50-1/200.
Background The enzyme tyrosine hydroxylase (TH), also designated tyrosine 3-monooxygenase (TY3H), catalyzes the conversion of tyrosine to L-dopa, which is the rate limiting step in the biosynthesis of catecholamines such as dopamine, adrenalin and noradrenalin. TH is thought to play a role in the pathogenesis of Parkinson’s disease, which is associated with reduced dopamine levels. Two transcription factor binding sites in the proximal region of the TH gene, the TPA-responsive element (TRE) and the c-AMP responsive element (CRE), have been implicated in the complex regulation of the TH gene. TH is also known to be upregulated by the glia maturation factor (GMF), a Cdc 10/SWI6 motif-containing protein called V-1, and a variety of additional compounds.
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Buffer System:
Phosphate buffered saline (PBS), pH 7.2.
Preservatives:
0.05% sodium azide
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (expected):
Mouse and Rat.
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody detects endogenous levels of Tyrosine Hydroxylase protein.
(region surrounding Gln25)
Gene ID 7054

Accessory Products

Proteins and/or Positive Controls

Proteins for Tyrosine 3-monooxygenase (TH) (2 products)

Catalog No. Species Pres. Purity   Source  

Tyrosine 3-monooxygenase (TH) (transcript variant 2)

Tyrosine 3-monooxygenase (TH) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.

Tyrosine 3-monooxygenase (TH)

Western Blot: Tyrosine Hydroxylase Protein [NBP1-42461] - Novus Biologicals antibody NB300-109 was used to detect the protein on a Western Blot.  150ng of protein were added to the Western Blot. Human Purified
  Novus Biologicals Inc.

Positive controls for Tyrosine 3-monooxygenase (TH) (1 products)

Catalog No. Species Pres. Purity   Source  

TH overexpression lysate

TH overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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