AP02433PU-S Tyrosine-protein kinase JAK1 pTyr1022 antibody

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50 µg / €230.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat Tyrosine-protein kinase JAK1

AP02433PU-S

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Product Description for Tyrosine-protein kinase JAK1

Rabbit anti Human, Mouse, Rat Tyrosine-protein kinase JAK1.
Properties: pTyr1022
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for Tyrosine-protein kinase JAK1

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms JAK-1, JAK1A, JAK1B, Janus kinase 1
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Molecular weight 130 kDa (Predicted)
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P23458
Immunogen:
The antiserum was produced against synthesized phosphopeptide derived from Human JAK1 around the phosphorylation site of tyrosine 1022 (K-E-YP-Y-T).
GeneID:
3716
Property pTyr1022
Application Western blot (1/500~1/1000). 
Immunohistochemistry (1/50~1/100).
Concentration 1.0 mg/ml
General Readings
  1. Zheng H, Hu P, Quinn DF, Wang YK. Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography. Mol Cell Proteomics. 2005 Jun;4(6):721-30. Epub 2005 Jan 19. PubMed PMID: 15659558.
  2. Wang R, Griffin PR, Small EC, Thompson JE. Mechanism of Janus kinase 3-catalyzed phosphorylation of a Janus kinase 1 activation loop peptide. Arch Biochem Biophys. 2003 Feb 1;410(1):7-15. PubMed PMID: 12559972.
  3. Cha Y, Moon BH, Lee MO, Ahn HJ, Lee HJ, Lee KA, et al. Zap70 functions to maintain stemness of mouse embryonic stem cells by negatively regulating Jak1/Stat3/c-Myc signaling. Stem Cells. 2010 Sep;28(9):1476-86. doi: 10.1002/stem.470. PubMed PMID: 20641039. (Free PMC Article available, 6 images available)
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography
Buffer System:
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol
State:
Liquid purified IgG fraction
Aff - Purified
Specificity
Specificity:
The antibody was affinity-purified from rabbit antiserum by Affinity-Chromatography using epitope-specific phosphopeptide.
The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
This antibody detects endogenous levels of JAK1 only when phosphorylated at tyrosine 1022.
Species:
Human, Rat and Mouse.
Gene ID 3716

Accessory Products

Proteins and/or Positive Controls

Proteins for Tyrosine-protein kinase JAK1 (4 products)

Catalog No. Species Pres. Purity   Source  

Tyrosine-protein kinase JAK1

Tyrosine-protein kinase JAK1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €788.00
  OriGene Technologies, Inc.

Tyrosine-protein kinase JAK1

Tyrosine-protein kinase JAK1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Tyrosine-protein kinase JAK1

Tyrosine-protein kinase JAK1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Tyrosine-protein kinase JAK1

Tyrosine-protein kinase JAK1 Human
  Abnova Taiwan Corp.

Positive controls for Tyrosine-protein kinase JAK1 (2 products)

Catalog No. Species Pres. Purity   Source  

JAK1 Lysate

Western Blot: JAK1 Lysate [NBL1-12093] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for JAK1
  Novus Biologicals Inc.

JAK1 overexpression lysate

JAK1 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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