AP55701PU-N Tyrosine-protein kinase JAK2 pTyr570 antibody

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0.1 mg / €340.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human, Mouse, Rat Tyrosine-protein kinase JAK2

Product Description for Tyrosine-protein kinase JAK2

Rabbit anti Human, Mouse, Rat Tyrosine-protein kinase JAK2.
Properties: pTyr570
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for Tyrosine-protein kinase JAK2

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms JAK-2, Janus kinase 2
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Molecular weight 125 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O60674
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 570(G-D-Y(p)-G-Q) derived from Human JAK2 (KLH-conjugated)
GeneID:
3717
Property pTyr570
Application Western blot: 1:500~1:1000.
Background Plays a role in leptin signaling and control of body weight.
Concentration 1.0 mg/ml
General Readings
  1. Saltzman A, Stone M, Franks C, Searfoss G, Munro R, Jaye M, et al. Cloning and characterization of human Jak-2 kinase: high mRNA expression in immune cells and muscle tissue. Biochem Biophys Res Commun. 1998 May 29;246(3):627-33. PubMed PMID: 9618263.
  2. Dalal I, Arpaia E, Dadi H, Kulkarni S, Squire J, Roifman CM. Cloning and characterization of the human homolog of mouse Jak2. Blood. 1998 Feb 1;91(3):844-51. PubMed PMID: 9446644.
  3. Peeters P, Raynaud SD, Cools J, Wlodarska I, Grosgeorge J, Philip P, et al. Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia. Blood. 1997 Oct 1;90(7):2535-40. PubMed PMID: 9326218.
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography using epitope-specific peptide
Buffer System:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, Mouse, Rat
Specificity
Specificity:
The antibody detects endogenous levels of JAK2 only when phosphorylated at tyrosine 750.

Accessory Products

Proteins and/or Positive Controls

Proteins for Tyrosine-protein kinase JAK2 (9 products)

Catalog No. Species Pres. Purity   Source  

Tyrosine-protein kinase JAK2

Tyrosine-protein kinase JAK2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Tyrosine-protein kinase JAK2 (1014-1132, His-tag)

Tyrosine-protein kinase JAK2 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  OriGene Technologies GmbH

Tyrosine-protein kinase JAK2 (1014-1132, His-tag)

Tyrosine-protein kinase JAK2 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  OriGene Technologies GmbH

Tyrosine-protein kinase JAK2

Tyrosine-protein kinase JAK2 Human
  Abnova Taiwan Corp.

Tyrosine-protein kinase JAK2

Tyrosine-protein kinase JAK2 Human
  Abnova Taiwan Corp.

Tyrosine-protein kinase JAK2

Tyrosine-protein kinase JAK2 Human
  Abnova Taiwan Corp.

Tyrosine-protein kinase JAK2

Tyrosine-protein kinase JAK2 Human
  Abnova Taiwan Corp.

Tyrosine-protein kinase JAK2

Tyrosine-protein kinase JAK2 Human
  Abnova Taiwan Corp.

Tyrosine-protein kinase JAK2

Tyrosine-protein kinase JAK2 Human
  Abnova Taiwan Corp.
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