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ARP43025_T100 UBE2L3 / UBCH7 antibody

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Rabbit anti Bovine, Canine, Chicken, Human, Mouse, Porcine, Rat, Zebrafish, African clawed frog UBE2L3 / UBCH7

ARP43025_T100

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  • ARP43025_T100

Product Description for UBE2L3 / UBCH7

Rabbit anti Bovine, Canine, Chicken, Human, Mouse, Porcine, Rat, Zebrafish, African clawed frog UBE2L3 / UBCH7.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for UBE2L3 / UBCH7

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms E2-F1, L-UBC, UBCE7, Ubiquitin carrier protein L3, Ubiquitin-conjugating enzyme E2 L3, Ubiquitin-protein ligase L3
Presentation Aff - Purified
Reactivity African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rt, Ze
Applications P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer AVIVA Systems Biology

Datasheet Extract

Immunogen
Swiss Prot Num:
P68036
Immunogen:
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human UBE2L3 with an internal ID of S13802
GeneID:
7332
Add. information Rabbit IgG purified by protein A chromatography. 75kDa, 75kDa
Application Suggested dilution at 1.25 ELISA titre using peptide based assay: 1:312500
Background The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.
General Readings Yao,Y.L. (2003) J. Biol. Chem. 278 (43), 42560-42568
Storage Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 ?l of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20DegC. Avoid repeat freeze-thaw cycles.
Format
Purification:
Rabbit IgG purified by protein A chromatography.
Buffer System:
Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 ?l of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20DegC. Avoid repeat freeze-thaw cycles.
State:
Aff - Purified
Specificity
Species:
Human
Gene ID 7332

Accessory Products

Proteins and/or Positive Controls

Proteins for UBE2L3 / UBCH7 (10 products)

Catalog No. Species Pres. Purity   Source  

UBE2L3 / UBCH7 (transcript variant 1)

UBE2L3 / UBCH7 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

UBE2L3 / UBCH7 (His-tagged)

UBE2L3 / UBCH7 Human Purified > 95.0% as determined by: 
(a) Analysis by RP-HPLC. 
(b) Analysis by SDS-PAGE.
E. coli
  Acris Antibodies GmbH

UBE2L3 / UBCH7 (His-tagged)

UBE2L3 / UBCH7 Human Purified > 95.0% as determined by: 
(a) Analysis by RP-HPLC. 
(b) Analysis by SDS-PAGE.
E. coli
  Acris Antibodies GmbH

UBE2L3 / UBCH7 (His-tagged)

UBE2L3 / UBCH7 Human Purified > 95.0% as determined by: 
(a) Analysis by RP-HPLC. 
(b) Analysis by SDS-PAGE.
E. coli
  Acris Antibodies GmbH

UBE2L3 / UBCH7

UBE2L3 / UBCH7 Human in vitro transl.
  Abnova Taiwan Corp.

UBE2L3 / UBCH7

UBE2L3 / UBCH7 Human in vitro transl.
  Abnova Taiwan Corp.

UBE2L3 / UBCH7

UBE2L3 / UBCH7 Human in vitro transl.
  Abnova Taiwan Corp.

UBE2L3 / UBCH7

UBE2L3 / UBCH7 Human
  Abnova Taiwan Corp.

UBE2L3 / UBCH7

UBE2L3 / UBCH7 Human
  Abnova Taiwan Corp.

UBE2L3 / UBCH7

SDS-Page: Aprataxin Protein [NBP1-40397] - Aprataxin, 23.9kDa (205aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE Liquid
  Novus Biologicals Inc.

Positive controls for UBE2L3 / UBCH7 (1 products)

Catalog No. Species Pres. Purity   Source  

Ube2L3 Lysate

Western Blot: Ube2L3 Lysate [NBL1-17537] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for UBE2L3
  Novus Biologicals Inc.
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