AP16521PU-N UNC13D antibody

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0.1 mg / €380.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Goat anti Canine, Human, Mouse, Rat UNC13D

AP16521PU-N

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  • AP16521PU-N

Product Description for UNC13D

Goat anti Canine, Human, Mouse, Rat UNC13D.
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for UNC13D

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms Munc13-4, Protein unc-13 homolog D
Presentation Aff - Purified
Reactivity Can, Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Goat
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q70J99
Immunogen:
Peptide with sequence C-ETQKHKKDLHPLFD, from the internal region of the protein sequence
GeneID:
201294
Application ELISA: 1/128000.
Western Blot: 1 - 3 µg/ml.
Immunohistochemistry on paraffin sections: 2.5 µg/ml.
Background Secretion of the contents of cytolytic granules at the immunologic synapse is a highly regulated process essential for lymphocyte cytotoxicity. This process requires the rapid transfer of perforin containing lytic granules to the target cell interface, followed by their docking and fusion with the plasma membrane. Munc 13-4 localises with cytotoxic granules at the immunologic synapse. Munc 13-4 is essential for the priming step of cytolytic granule secretion preceding vesicle membrane fusion. There are two named isoforms.
Concentration 0.5 mg/ml
General Readings
  1. Zur Stadt U, Beutel K, Kolberg S, Schneppenheim R, Kabisch H, Janka G, et al. Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A. Hum Mutat. 2006 Jan;27(1):62-8. PubMed PMID: 16278825.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography
Buffer System:
Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
State:
Liquid purified Ig
Aff - Purified
Species Reactivity
Species reactivity (expected):
Mouse, Rat, Canine.
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody reacts to Munc13-4 / UNC13D.
Gene ID 201294

Accessory Products

Proteins and/or Positive Controls

Proteins for UNC13D (3 products)

Catalog No. Species Pres. Purity   Source  

UNC13D

UNC13D Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €788.00
  OriGene Technologies, Inc.

UNC13D

UNC13D Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

UNC13D

UNC13D Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Positive controls for UNC13D (3 products)

Catalog No. Species Pres. Purity   Source  

Munc 13-4 Lysate

Western Blot: Munc 13-4 Lysate [NBL1-17611] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for UNC13D
  Novus Biologicals Inc.

UNC13D 293T Cell Transient Overexpression Lysate(Denatured)

UNC13D 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

UNC13D overexpression lysate

UNC13D overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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