discontinued

AP30976PU-N Unc93a antibody

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0.1 mg / €360.00

Quick Overview

Rabbit anti Human Unc93a

Product Description for Unc93a

Rabbit anti Human Unc93a.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Unc93a

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms homolog of C. elegans Unc93
Presentation Aff - Purified
Reactivity Hu
Applications E, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q4QQJ4
Immunogen:
Unc93a antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human Unc93a.
GeneID:
54346
Control peptide AP30976CP-N
Add. information Blocking peptide available: AP30976CP-N
Application ELISA.
Western blot: 0.5 – 1 μg/ml.
Background Unc93a, a human homolog of the C. elegans Unc93 gene, was initially identified by the sequencing of chromosome 6q27 at D6S193 as loss at this region correlated with sporadic ovarian cancer. Further analysis however, showed no tumor suppressor role for Unc93a. Unlike Unc93b, another homolog of the C. elegans Unc93 gene that is crucial for Toll-like receptor (TLR) signaling, the function of Unc93a is unknown. It is expressed in testis, small intestine, spleen, prostate and ovary. Two isoforms of Unc93a are known to exist.
General Readings
  1. Liu Y, Dodds P, Emilion G, et al. The human homolog of unc-93 maps to chromosome 6q27.
  2. Massey DC, Parkes M. Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease. Autophagy. 2007 Nov-Dec;3(6):649-51. Epub 2007 Sep 24. PubMed PMID: 17921695.
Storage Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography
Buffer System:
PBS containing 0.02% sodium azide
State:
Liquid Íg fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human
Specificity
Specificity:
This antibody detects Unc93a.
The antibody will not cross-react with Unc93b.
Gene ID 54346

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