discontinued

AM05150PU-N uPA / PLAU antibody

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Mouse anti Mouse uPA / PLAU B042M

Product Description for uPA / PLAU

Mouse anti Mouse uPA / PLAU B042M.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for uPA / PLAU

Product Category Primary Antibodies
Target Category
Quantity 1 mg
Synonyms U-plasminogen activator, Urokinase, Urokinase-type plasminogen activator, Urokinase-type plasminogen activator chain B, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A
Presentation Purified
Reactivity Ms
Applications WB
Clonality Monoclonal
Clone B042M
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P06869
Immunogen:
Mouse Urokinase
GeneID:
18792
Isotype control AM03095PU-N
Application Western Blot.
Background Urokinase is a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in the Urokinase gene may be associated with late onset Alzheimer disease and also with decreased affinity for fibrin binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg Val bond in plasminogen. The proprotein is cleaved at a Lys Ile bond by plasmin to form a two chain derivative in which a single disulfide bond connects the amino terminal A chain to the catalytically active, carboxy terminal B chain. This two chain derivative is also called HMW uPA (high molecular weight uPA). HMW uPA can be further processed into LMW uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino terminal fragment. LMW uPA is proteolytically active but does not bind to the uPA receptor.
Storage Store the antibody at -70°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
>98% pure (SDS-PAGE). Produced in a uPA knockout mouse. Protein A chromatography
Buffer System:
0.05M Sodium Phosphate, pH 7.4 containing 0.15M Sodium chloride
State:
Liquid purified Ig
Purified
Specificity
Specificity:
This antibody reacts to Urokinase (uPA).
Species:
Mouse.
Gene ID 18792

Accessory Products

Proteins and/or Positive Controls

Proteins for uPA / PLAU (1 products)

Catalog No. Species Pres. Purity   Source  

uPA / PLAU

uPA / PLAU Mouse Purified >98% pure (SDS-PAGE). 95% high molecular weight. Purified by column chromatography
  Acris Antibodies GmbH
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