AP20580PU-N uPA / PLAU antibody

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0.1 mg / €350.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human uPA / PLAU

Product Description for uPA / PLAU

Rabbit anti Human uPA / PLAU.
Presentation: Aff - Purified
Product is tested for Paraffin Sections.

Properties for uPA / PLAU

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms U-plasminogen activator, Urokinase, Urokinase-type plasminogen activator, Urokinase-type plasminogen activator chain B, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A
Presentation Aff - Purified
Reactivity Hu
Applications P
Clonality Polyclonal
Host Rabbit
Molecular weight ~ 48 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P00749
Immunogen:
Synthetic peptide, corresponding to amino acids 211-260 of Human uPA.
GeneID:
5328
Application Immunohistochemistry on paraffin sections: 1/50 - 1/200.
Background uPA (urokinase-type plasminogen activator) and tPA (tissue plasminogen activator) are serine proteases that are members of the trypsin family, and they are essential to the intrinsic coagulation system. tPA is primarily involved in fibrinolysis, whereas uPA principally mediates cell migration and tissue remodeling processes. uPA and tPA are responsible for cleaving plasminogen, a large serum β-globulin that is deposited on the Fibrin strands within a thrombus. uPA and tPA preferentially target plasminogen at the Arg-Val bond to produce plasmin (also designated fibrinolysin), which is a trypsin-like enzyme that acts on Arg-Lys bonds in Fibrin and Fibrinogen and contributes to the systematic activation of the coagulation cascade. uPA and tPA each consist of two chains that are designated A and B. The A chain of uPA can be cleaved, resulting in low and high molecular mass forms. uPA and tPA are regulated by the serpin family members PAI-1 and PAI-2, which are serine proteinase inhibitors that complex with uPA, tPA and other targeted proteinases and then slowly disassociate to produce cleaved species that fold into stable inactive conformations.
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography (> 95% (by SDS-PAGE)
Buffer System:
Phosphate buffered saline (PBS), pH 7.2.
Preservatives:
0.05% sodium azide
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody detects endogenous levels of uPA protein.
(region surrounding Leu239)
Gene ID 5328

Accessory Products

Proteins and/or Positive Controls

Proteins for uPA / PLAU (16 products)

Catalog No. Species Pres. Purity   Source  

uPA / PLAU (transcript variant 1)

uPA / PLAU Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

uPA / PLAU (transcript variant 1)

uPA / PLAU Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

uPA / PLAU (HMW)

uPA / PLAU Human Purified >98% pure (SDS-PAGE). 95% high molecular weight. Purified by column chromatography Urine
  Acris Antibodies GmbH

uPA / PLAU (LMW Isoform)

uPA / PLAU Human Purified >98% pure (SDS-PAGE). >98% low molecular weight. Column chromatography Urine
  Acris Antibodies GmbH

uPA / PLAU

uPA / PLAU Human Purified > 90.0% as determined by SDS-PAGE. 
Contaminents: Free of: Hepatitis B surface antigen, Hepatitis C antibody and HIV I and II.
  Acris Antibodies GmbH

uPA / PLAU

uPA / PLAU Human Purified > 90.0% as determined by SDS-PAGE. 
Contaminents: Free of: Hepatitis B surface antigen, Hepatitis C antibody and HIV I and II.
  Acris Antibodies GmbH

uPA / PLAU

uPA / PLAU Human Purified > 90.0% as determined by SDS-PAGE. 
Contaminents: Free of: Hepatitis B surface antigen, Hepatitis C antibody and HIV I and II.
  Acris Antibodies GmbH

uPA / PLAU

uPA / PLAU Human Purified > 90 % Free of Hepatitis B surface antigen, Hepatitis C antibody and HIV I and II.
Purity is greater than 90.0% as determined by SDS-PAGE.
Urine
  Acris Antibodies GmbH

uPA / PLAU

uPA / PLAU Human Purified > 90 % Free of Hepatitis B surface antigen, Hepatitis C antibody and HIV I and II.
Purity is greater than 90.0% as determined by SDS-PAGE.
Urine
  Acris Antibodies GmbH

uPA / PLAU

uPA / PLAU Human Purified > 90 % Free of Hepatitis B surface antigen, Hepatitis C antibody and HIV I and II.
Purity is greater than 90.0% as determined by SDS-PAGE.
Urine
  Acris Antibodies GmbH

uPA / PLAU

uPA / PLAU Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

uPA / PLAU

uPA / PLAU Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

uPA / PLAU

uPA / PLAU Human
  Abnova Taiwan Corp.

uPA / PLAU

uPA / PLAU Human
  Abnova Taiwan Corp.

uPA / PLAU

uPA / PLAU Human
  Abnova Taiwan Corp.

uPA / PLAU

uPA / PLAU Human
  Abnova Taiwan Corp.

Positive controls for uPA / PLAU (1 products)

Catalog No. Species Pres. Purity   Source  

Urokinase Lysate

Western Blot: Urokinase Lysate [NBL1-14486] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for PLAU
  Novus Biologicals Inc.
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