discontinued

NB110-81554 UPAR antibody

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0.05mg/0.05ml / €330.00

Quick Overview

Chicken anti Human UPAR

NB110-81554

Product Description for UPAR

Chicken anti Human UPAR.
Product is tested for Western blot / Immunoblot.

Properties for UPAR

Product Category Primary Antibodies
Quantity 0.05mg/0.05ml
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Chicken
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
94-300
Application Western Blot
Background This protein is the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Concentration 1 mg/ml
General Readings Memarzadeh, S.; Kozak, K. R.; Chang, L.; Natarajan, S.; Shintaku, P.; Reddy, S. T.; Farias-Eisner, R. : Urokinase plasminogen activator receptor: prognostic biomarker for endometrial cancer. Proc. Nat. Acad. Sci. 99: 10647-10652, 2002. Note: Erratum: Proc. Nat. Acad. Sci. 99: 12501 only, 2002.
Storage 4 degree C for short term (weeks) and -20 degree C for long term. Avoid frequent freeze and thaw.
Format
Buffer System:
Phosphate-Buffered Saline. No preservatives added
Specificity
Species:
Human. Not tested in other species.

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