TA306333 Uracil-DNA glycosylase 2 / Cyclin-O antibody

Rabbit Polyclonal UNG2 Antibody

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0.1 mg / €371.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human, Mouse, Rat Uracil-DNA glycosylase 2 / Cyclin-O

Product Description for Uracil-DNA glycosylase 2 / Cyclin-O

Rabbit anti Human, Mouse, Rat Uracil-DNA glycosylase 2 / Cyclin-O.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for Uracil-DNA glycosylase 2 / Cyclin-O

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms CCNO, Cyclin-like uracil-DNA glycosylase, UDG2, UNG2
Presentation Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P22674
Immunogen:
UNG2 antibody was raised against a 14 amino acid peptide from near the amino terminus of human UNG2.
GeneID:
10309
Application WB: 1 - 2 ug/mL
Background The human uracil-D glycosylase (UNG) gene encodes both mitochondrial (UNG1) and nuclear (UNG2) forms through differentially regulated promotes and altertive splicing. UNG2 is the major enzyme in the base excision repair pathway that removes uracil residues from D that arise through either misincorporation during replication or cytosine deamition. UNG2 can also be bound by the HIV-1 integrase and incorporated into the virion particle, suggesting that it is required to remove uracils from the viral genome. As the intrinsic antiviral protein APOBEC3G generates numerous uracils in the HIV genome during its replication, it may be that the UNG2 contributes to the APOBEC3G-mediated loss of infectivity by generating abasic sites in the viral genome. This UNG2 antibody will not cross-react with UNG1.
Format
Purification:
Affinity chromatography purified via peptide column
Buffer System:
PBS containing 0.02% sodium azide.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Positive controls for Uracil-DNA glycosylase 2 / Cyclin-O (1 products)

Catalog No. Species Pres. Purity   Source  

CCNO overexpression lysate

CCNO overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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