DM3227 Urokinase-type Plasminogen Activator (uPA) antibody

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Mouse anti Human Urokinase-type Plasminogen Activator (uPA) 4-19


Product Description for Urokinase-type Plasminogen Activator (uPA)

Mouse anti Human Urokinase-type Plasminogen Activator (uPA) 4-19.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for Urokinase-type Plasminogen Activator (uPA)

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Hu
Applications WB
Clonality Monoclonal
Clone 4-19
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Biomeda

Datasheet Extract

Native purified human ~35kD uPA.
Isotype control AM03095PU-N, SM10P (for use in human samples)
Application Effect on Dissulution of Fibrin: None (1). Western Blotting (1-2 µg/ml for 2 hrs at RT. Recommended positive control: Conditioned, serum-free medium from (TPA-treated) human fetal lung cell line HFL-1). Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
Concentration 0.2 mg/ml
General Readings
  1. Birkedal-Hansen H et. al ., Immunological Investigation
Storage Store the antibody at 4°C. Do not freeze! Shelf life: one year from despatch.
Urokinase-type Plasminogen Activator (uPA) is secreted from cells as a precursor which is activated to the two chain form consisting of an alpha- and beta-chain. Detects human uPA (35 & 55 kD) by Western blot. Cellular Localization: Cell Surface, Cytoplasmic, Extracellular Matrix.

Mol. Wt of Antigen: ~35kD (active) and ~55kD (proform)

Notes: In WB this antibody recognises both (35 & 55kD) forms of uPA.

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