discontinued

AP00177PU-N Urokinase-type Plasminogen Activator (uPAR) antibody

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0.1 mg / €420.00

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Goat anti Human Urokinase-type Plasminogen Activator (uPAR)

AP00177PU-N

Product Description for Urokinase-type Plasminogen Activator (uPAR)

Goat anti Human Urokinase-type Plasminogen Activator (uPAR).
Presentation: Purified
Product is tested for Functional assay, Immunoprecipitation, Western blot / Immunoblot.

Properties for Urokinase-type Plasminogen Activator (uPAR)

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Hu
Applications FN, IP, WB
Clonality Polyclonal
Host Goat
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Recombinant full length uPAR protein
Application Neutralization (2 - 4 μg/ml).
Western blotting (0.5 - 1 μg/ml).
Immunoprecipitation (5 - 10 μg/ml).
Background uPAR (Urokinase plasminogen activator receptor) is a 55 kDa glycoprotein I-anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum β-globulin, plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.
Concentration 0.5 mg/ml
Storage Store at -20 °C. For long term storage, aliquot and freeze at -70 °C. Avoid repeated freeze/defrost cycles. Shelf life: One year from despatch.
Format
Purification:
purified
Buffer System:
Supplied in 1X phosphate-buffered saline (PBS)
State:
liquid
Purified
Specificity
Specificity:
The antibody recognizes 55 kDa uPAR.
Species:
Human.

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