TA306580 UROP11 antibody

Rabbit Polyclonal UROP11 Antibody

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0.1 mg / €371.00
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Quick Overview

Rabbit anti Human, Mouse, Rat UROP11

Product Description for UROP11

Rabbit anti Human, Mouse, Rat UROP11.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for UROP11

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Upregulated obese product 11
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Swiss Prot Num:
UROP11 antibody was raised against a 12 amino acid peptide near the center of the mouse UROP11.
Add. information Blocking peptide available: AP30982CP-N
Application ELISA.
Western blot: 1 – 2 μg/ml.
Background Upregulated obese product 11 (UROP11) was isolated from subtractive library for mouse hypothalamus. It is detected in numerous tissues and is upregulated in the hypothalamus and adipocytes in obese mice. UROP11 is also observed in human neural and lymphoid tissues; its expression appears to be regulated by the level of lymphoid activation. Urop11 expression is strongly upregulated both in vivo in mouse hypothalamus and in vitro in mouse neural cell lines after treatment with leptin, indicating Urop11 is a target of leptin activity and thus may play a role in obesity. Despite its predicted molecular weight, UROP11 often migrates at a much higher apparent size in SDS-PAGE.
General Readings
  1. Verlaeten O, Casery C, Cavagna S, Naville D, Giraudon P, Belin MF, et al. Identification of Urop11, a novel leptin-modulated gene that is upregulated in the hypothalamus of mice with virus-induced obesity. J Mol Endocrinol. 2007 Feb;38(1-2):3-17. PubMed PMID: 17242166.
Storage Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Affinity chromatography
Buffer System:
PBS containing 0.02% sodium azide
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, mouse, rat
This antibody detects UROP11.

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