NBP1-28407 VCAM1 (1.G11B1) antibody

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1 ml / €500.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Mouse anti Human VCAM1 (1.G11B1) 1.G11B1

NBP1-28407

Product Description for VCAM1 (1.G11B1)

Mouse anti Human VCAM1 (1.G11B1) 1.G11B1.
Presentation: PE
Product is tested for Frozen Sections, Enzyme Immunoassay, Flow Cytometry, Paraffin Sections, Western blot / Immunoblot.

Properties for VCAM1 (1.G11B1)

Product Category Primary Antibodies
Quantity 1 ml
Synonyms anti-CD 106 antibody, anti-CD106 Antigen antibody, anti-CD106 antibody, anti-DKFZp779G2333 antibody, anti-INCAM 100 antibody, anti-L1CAM antibody, anti-MGC99561 antibody, anti-VCAM 1 antibody, anti-Vascular Cell Adhesion Molecule 1 antibody, anti-Vascular cell adhesion protein 1 antibody
Presentation PE
Reactivity Hu
Applications C, E, F, P, WB
Clonality Monoclonal
Clone 1.G11B1
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Isotype control SM10R (for use in human samples)
Add. information Protect conjugated forms from light.
Application ELISA, flow cytometry / FACS analysis, Immunohistochemistry-Frozen, Western Blot, Flow cytometry / FACS analysis, ELISA, Western Blot and Immunohistochemistry-Frozen , flow cytometry / FACS analysis 10 uL/1^6 cells, ELISA , Western Blot , Immunohistochemistry-Frozen
Background CD106, also known as INCAM-1, is a 100-110 kDa vascular adhesion cell adhesion molecule-1 (VCAM-1) that is member of the immunoglobulin superfamily. CD106 is expressed predominantly on cytokine activated vascular endothelium but has also been identified on interfollicular dendritic cells, some macrophages and bone marrow stromal cells. Endothelial CD106 binds the integrins alpha4beta1 (CD49d/CD29, VLA-4) and alpha4beta7 and contributes to extravasation of lymphocytes, monocytes, basophils and eosinophils (but not neutrophils) from blood vessels, particularly at sites of inflammation. Unlike the beta2 integrins, the CD106-VLA-4 interaction can mediate both the initial tethering and rolling of lymphocytes on endothelium as well as their subsequent arrest and firm adhesion. CD106 expressed on non-vascular tissues has been implicated in the interaction of hematopoietic progenitors with bone marrow stromal cells, B cell binding to follicular dendritic cells, costimulation of T cells, and embryonic development. The monoclonal antibody 1.G11B1 inhibits in vitro binding of lymphocytes and monocytes to VCAM-1 on stimulated endothelium. (1-4)
Storage Store at 4C. Do not freeze.
Format
Label:
R-Phycoerythrin
PE
Purification:
IgG purified
Buffer System:
No Preservative
Purity:
IgG purified
Specificity
Species:
Human

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