DP3511P VEGFR-3 / Flt-4 antibody

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50 µg / €300.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human VEGFR-3 / Flt-4

DP3511P

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Product Description for VEGFR-3 / Flt-4

Rabbit anti Human VEGFR-3 / Flt-4.
Presentation: Aff - Purified
Product is tested for Flow Cytometry, Frozen Sections, Enzyme Immunoassay, Immunoprecipitation, Western blot / Immunoblot.

Properties for VEGFR-3 / Flt-4

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms FLT4, Tyrosine-protein kinase receptor FLT4, VEGF Receptor 3, VEGFR3, Vascular endothelial growth factor receptor 3
Presentation Aff - Purified
Reactivity Hu
Applications C, E, F, IP, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P35916
Immunogen:
Recombinant human soluble FLT-4 protein (110 kDa).
GeneID:
2324
Application ELISA: 0.5-1.5 µg/ml, allows the detection of 0.25-0.5 ng/well rhVEGFR-3/FLT-4.
Western Blot: 0.5-1 µg/ml, it will detect approximately 5 ng/lane of rh VEGFR-3/FLT-4 under reducing conditions depending on the visualisation method.
Immunoprecipitation: 1-5 µg/ml lysate or reaction volume. 
FACS: Use 1-5 μg/ml
Immunofluorescence.
Immunohistochemistry on Frozen sections.
Background The sVEGFR-3/FLT-4 monomers have a mass of approximately 120kDa. The soluble receptor protein consists of all 7 extracellular domains (Met1-Glu774). All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases (RTKs) characterised by the seven immunoglobulin-like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular and lymphatic endothelial cells and to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis and lymphangiogenesis. The FLT-4 cDNA encodes a 1298 amino acid (aa) residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain and a 482aa residue cytoplasmic domain. Both VEGF family members VEGF-C and VEGF-D have been shown to bind and activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial
General Readings
  • Joukov et al., EMBO J 15 :290, 1996.
  • Kukk et al., Development 122 :3829, 1996.
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein A Affinity Chromatography
Buffer System:
PBS, pH 7.4 containing no preservatives or stabilizers
State:
Lyophilized purified Ig fraction
Aff - Purified
Reconstitution:
Restore in sterile water to a concentration of 0.1-1 mg/ml.
Specificity
Specificity:
The antibody will detect human VEGFR-3/FLT-4.
In Western blots, this antibody shows a moderate cross-reactivity with VEGFR-2/KDR and a weak cross-reactivity with VEGFR-1/Flt-1.
Species:
Human.
Gene ID 2324
FocusOn and Reviews
FocusOns:

Accessory Products

Proteins and/or Positive Controls

Proteins for VEGFR-3 / Flt-4 (10 products)

Catalog No. Species Pres. Purity   Source  

VEGFR-3 / Flt-4 (C-term DDK/His tag, transcript variant 1)

VEGFR-3 / Flt-4 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

VEGFR-3 / Flt-4 (His-tagged)

VEGFR-3 / Flt-4 Human Purified > 90 % by SDS-PAGE and visualised by silver stain Insect cells
10 µg / €230.00
  OriGene Technologies GmbH

VEGFR-3 / Flt-4 (His-tagged)

VEGFR-3 / Flt-4 Human Purified > 90 % by SDS-PAGE and visualised by silver stain Insect cells
5 µg / €190.00
  OriGene Technologies GmbH

VEGFR-3 / Flt-4 (His-tag)

VEGFR-3 / Flt-4 Human Purified > 90 % by SDS-PAGE and visualised by silver stain Insect cells
50 µg / €380.00
  OriGene Technologies GmbH

VEGFR-3 / Flt-4 (Fc Chimera)

VEGFR-3 / Flt-4 Human Purified > 90 % by SDS-PAGE and visualised by silver stain. Insect cells
10 µg / €190.00
  OriGene Technologies GmbH

VEGFR-3 / Flt-4 (Fc Chimera)

VEGFR-3 / Flt-4 Human Purified > 90 % by SDS-PAGE and visualised by silver stain. Insect cells
50 µg / €350.00
  OriGene Technologies GmbH

VEGFR-3 / Flt-4

VEGFR-3 / Flt-4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

VEGFR-3 / Flt-4

VEGFR-3 / Flt-4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

VEGFR-3 / Flt-4

VEGFR-3 / Flt-4 Human
  Abnova Taiwan Corp.

VEGFR-3 / Flt-4

VEGFR-3 / Flt-4 Human
  Abnova Taiwan Corp.

Positive controls for VEGFR-3 / Flt-4 (1 products)

Catalog No. Species Pres. Purity   Source  

FLT4 overexpression lysate

FLT4 overexpression lysate
0.1 mg / €495.00
  OriGene Technologies, Inc.
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