discontinued

GTX13055 vH RAS [Y13-238] antibody

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50 µg / €410.00

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Rat anti Human, Mouse, Rat vH RAS [Y13-238] Y13-238

GTX13055

Product Description for vH RAS [Y13-238]

Rat anti Human, Mouse, Rat vH RAS [Y13-238] Y13-238.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Immunoprecipitation.

Properties for vH RAS [Y13-238]

Product Category Primary Antibodies
Quantity 50 µg
Presentation Purified
Reactivity Hu, Ms, Rt
Applications ICC/IF, IP
Clonality Monoclonal
Clone Y13-238
Host Rat
Isotype IgG2a
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9BR65
Immunogen:
Recombinant p21 protein (Human).
GeneID:
3265
Isotype control SM15PX
Application IF, IP
Background RAS proteins are signal-transducing, guanine nucleotide-binding proteins that appear to function as a branchpoint in signal transduction. RAS coordinates the activity of multiple signalling pathways, regulating diverse cellular functions including cell growth, differentiation and apoptosis. The human RAS gene family consists of three identified members which encode proteins of 21 kDa. Human cH RAS and cK RAS are the cellular homologs of vH- and vK RAS originally isolated from Harvey and Kirsten strains of rat sarcoma viruses. The third family member is designated cN RAS. Normal cellular ras genes are referred to as protooncogenes and have the potential for activation to oncogenes by mutations occurring in codons 12, 13 and 61. Such mutated, activated and transforming ras genes have been identified and isolated from human tumors and cultured tumor cells. Although the expression patterns of ras proto-oncogene proteins in normal human tissues are known, similar information for activated ras oncogene encoded p21s and their relevance to human disease diagnosis and prognosis remains to be determined.
Concentration 0.1 mg/ml
Format
Purification:
Protein G purified
Buffer System:
Preservative: 0.1% Sodium Azide; Constituents: 0.2% gelatin, 0.05M Sodium Phosphate. pH 7.5
Purity:
Protein G purified
State:
Purified
Specificity
Specificity:
Cross-reacts with Human. Expected to cross-react with Mouse and Rat due to sequence homology. Not yet tested in other species.
Gene ID 3265

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