TA326633 VNN3 (C-term) antibody

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0.1 mg / €325.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat VNN3


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  • TA326633

Product Description for VNN3

Rabbit anti Human, Mouse, Rat VNN3.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for VNN3

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms HSA238982, Vanin 3, Vascular non-inflammatory molecule 3
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Molecular weight 55 kDa
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Swiss Prot Num:
19 amino acid synthetic peptide near the carboxy terminus of Human VNN3 (AP55466CP-N)
Property C-term
Add. information Blocking peptide available: AP55466CP-N
Application Western blot: 0.5-1 µg/ml. 
Positive Control: Human brain tissue lysate.
Background The vanin family is a novel group of ectoenzymes that function in tissue repair and plays a role in oxidative-stress response. As both secreted and membrane proteins, the vanin family members have been implicated as therapeutic targets in inflammatory disease. VNN3 (vascular non-inflammatory molecule 3), also known as Vanin3, is a 501 amino acid GPI-anchored amidohydrolase that is widely expressed and is found at highest levels in blood and liver. Induced by Th17 / Th1 type cytokines, VNN3 converts pantetheine into pantothenic acid. Containing one CN hydrolase domain, VNN3 is encoded by a gene that maps to human chromosome 6q23.2.
Concentration 1.0 mg/ml
General Readings
  1. Granjeaud S, Naquet P, Galland F. An ESTs description of the new Vanin gene family conserved from fly to human. Immunogenetics. 1999 Oct;49(11-12):964-72. PubMed PMID: 10501839.
  2. Jansen PA, Kamsteeg M, Rodijk-Olthuis D, van Vlijmen-Willems IM, de Jongh GJ, Bergers M, et al. Expression of the vanin gene family in normal and inflamed human skin: induction by proinflammatory cytokines. J Invest Dermatol. 2009 Sep;129(9):2167-74. doi: 10.1038/jid.2009.67. Epub 2009 Mar 26. PubMed PMID: 19322213.
  3. Nitto T, Inoue T, Node K. Alternative spliced variants in the pantetheinase family of genes expressed in human neutrophils. Gene. 2008 Dec 15;426(1-2):57-64. doi: 10.1016/j.gene.2008.08.019. Epub 2008 Sep 5. PubMed PMID: 18805469.
  4. Martin F, Malergue F, Pitari G, Philippe JM, Philips S, Chabret C, et al. Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes. Immunogenetics. 2001 May-Jun;53(4):296-306. PubMed PMID: 11491533.

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Affinity chromatography purified via peptide column
Buffer System:
PBS containing 0.02% Sodium Azide as preservative
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, Mouse, Rat.
Multiple isoforms of VNN3 are known to exist.

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