NBP1-30025 VPAC2 antibody

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Rabbit anti Human, Mouse, Rat VPAC2


Product Description for VPAC2

Rabbit anti Human, Mouse, Rat VPAC2.
Presentation: Serum
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for VPAC2

Product Category Primary Antibodies
Quantity 0.2 ml
Synonyms Anti-Helodermin preferring VIP receptor antibody, Anti-PACAP type III receptor antibody, Anti-Pituitary adenylate cyclase activating polype, Anti-VIP Receptor 2 antibody, Anti-VIP2R antibody, Anti-VPAC2 receptor antibody, Anti-Vasoactive intestinal peptide receptor 2 anti, Anti-Vasoactive intestinal polypeptide receptor 2, anti-FLJ16511 antibody, anti-VPAC2 antibody, anti-VPCAP2R antibody
Presentation Serum
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Synthetic peptide derived from an internal domain of human VIP-R2 protein
Add. information Reconstitute in 0.2 ml distilled water.
Research Areas: Neuroscience
Application immunohistochemistry, Western Blot, This antibody is useful in Western blot and Immunohistochemistry., immunohistochemistry 1/50 to 1/500, Western Blot 1/200 to 1/2 000
Background The vasoactive intestinal peptide (VIP) and the pituitary adenylate cylaseactivating polypeptide (PACAP) belong to a superfamily of peptide hormones that include glucagon, secretin and growth hormone releasing hormone. The effects of VIP and PACAP are mediated by three G-protein coupled receptors, VPAC1, VPAC2 and the PACAP receptor (also designated PAC1-R). The VPAC receptors have equal affinities for VIP and PACAP, which stimulate the activation of adenylyl cyclase. Both VPAC1, a 47 kDa protein, and VPAC2, a 65 kDa protein, are abundantly expressed in brain and T cells, where they modulate neuronal differentiation and T cell activation, respectively. The PACAP receptor is a seven transmembrane protein that produces at least eight isoforms by alternative splicing. Each isoform is associated with a specific signaling pathway and a specific expression pattern. The PACAP receptor, which is thought to play an integral role in brain development, preferentially binds PACAP in order to stimulate a cAMP-protein kinase A signaling pathway.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Whole antisera
Buffer System:
No Preservative
Whole antisera
Antiserum reacts specifically with human 49 kDa protein
Human, Mouse, Rat

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