NBP1-05975 WHSC2 antibody

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0.1 ml / €440.00
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Rabbit anti Human WHSC2

NBP1-05975

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  • NBP1-05975

Product Description for WHSC2

Rabbit anti Human WHSC2.
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Immunoprecipitation, Western blot / Immunoblot.

Properties for WHSC2

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms anti-NELF-A antibody, anti-NELFA antibody, anti-Negative elongation factor A antibody, anti-WHSC-2 antibody, anti-WHSC2 antibody, anti-Wolf-Hirschhorn syndrome candidate 2 antibody
Presentation Aff - Purified
Reactivity Hu
Applications IP, P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
The epitope recognized by this antibody maps to a region between residue 499 and 549 of human negative elongation factor A using the numbering given in entry BAB18651.1 (GeneID 7469).
Application immunoprecipitation, Western Blot, This antibody is useful for western blot and immunoprecipitation., Western Blot 1:2000-1:10000, immunoprecipitation 2-5 mcg/mg lysate,
Background This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq]
Concentration 1 mg/ml
Storage Store at 4C. Do not freeze.
Format
Purification:
Immunogen affinity purified
Buffer System:
0.09% Sodium Azide
Purity:
Immunogen affinity purified
State:
Aff - Purified
Specificity
Specificity:
NELFA
Species:
Human

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