NBP1-06538 WHSC2 antibody

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0.1 ml / €460.00

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Rabbit anti Human WHSC2


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  • NBP1-06538

Product Description for WHSC2

Rabbit anti Human WHSC2.
Presentation: Aff - Purified
Product is tested for Paraffin Sections.

Properties for WHSC2

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms anti-NELF-A antibody, anti-NELFA antibody, anti-Negative elongation factor A antibody, anti-WHSC-2 antibody, anti-WHSC2 antibody, anti-Wolf-Hirschhorn syndrome candidate 2 antibody
Presentation Aff - Purified
Reactivity Hu
Applications P
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

The epitope recognized by this antibody maps to a region between residue 499 and 549 of human negative elongation factor A using the numbering given in entry BAB18651.1 (GeneID 7469).
Application Immunohistochemistry-Paraffin, This antibody is useful for immunohistochemistry on paraffin sections. Epitope exposure with citrate bufferexposure is recommended. Epitope exposure with citrate buffer will enhance staining. Likely to work with frozen sections. In some cases, the antibody may be diluted further than indicated., Immunohistochemistry-Paraffin 1:100-1:500,
Background This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq]
Storage Store at 4C. Do not freeze.
Immunogen affinity purified
Buffer System:
0.09% Sodium Azide
Immunogen affinity purified
Aff - Purified

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